Abdu Lawan, Sani Rabi Yahaya
Department of Ophthalmology, Faculty of Medicine, Bayero University, Kano, Nigeria.
Ann Afr Med. 2014 Jul-Sep;13(3):134-7. doi: 10.4103/1596-3519.134417.
To determine macular volume and central foveal thickness measurements in normal eyes of healthy Nigerian adults using Stratus optical coherence tomography.
Consenting 100 adults Nigerians with normal eyes were recruited and examined using Carl Zeiss Stratus Optical Coherence Tomographer (OCT) machine Model 3000 software version 4.0. A fast macular thickness map scan protocol was employed. Central fovea is defined as locus of intersection of the radial scans. A default setting of six lines at 6 mm was used. Data was analyzed using the paired t-test for independence and linear regression.
There were 200 eyes of 100 subjects with mean age of 36.4 + 11.7 years (M: F = 3.3:1). The mean macula volume was 6.79 + 0.392 μm 3 . It was 6.861 ± 0.297 in males, 6.496 ± 0.520 in females and was statistically higher in males than females (P = 0.000). The mean central foveal thickness (MCFT) was 149.58 ± 32.470 μm. It was 154.49 ± 34.652 μm in males and 133.33 ± 15.315 μm in females. MCFT was significantly higher in males than females (P = 0.000).
Normal macular volume and central foveal thickness measurements in Nigerian adults is presented and is comparable to that of Indian and Chinese populations, but lower than reported in Caucasians.
使用Stratus光学相干断层扫描技术测定尼日利亚健康成年人正常眼睛的黄斑体积和中心凹厚度。
招募100名同意参与研究的尼日利亚正常眼睛成年人，使用卡尔·蔡司Stratus光学相干断层扫描仪（OCT）3000型、软件版本4.0进行检查。采用快速黄斑厚度图扫描方案。中心凹定义为径向扫描的交点位置。使用默认的6条6毫米线的设置。数据采用配对t检验进行独立性分析和线性回归分析。
100名受试者共200只眼睛，平均年龄为36.4±11.7岁（男∶女 = 3.3∶1）。平均黄斑体积为6.79±0.392μm³。男性为6.861±0.297，女性为6.496±0.520，男性显著高于女性（P = 0.000）。平均中心凹厚度（MCFT）为149.58±32.470μm。男性为154.49±34.652μm，女性为133.33±15.315μm。MCFT男性显著高于女性（P = 0.000）。
给出了尼日利亚成年人正常黄斑体积和中心凹厚度的测量结果，与印度和中国人群的结果相当，但低于白种人的报道值。
