Negative reinforcement via motivational withdrawal is the driving force behind the transition to addiction.
作者信息
George Olivier, Koob George F, Vendruscolo Leandro F
机构信息
Committee on the Neurobiology of Addictive Disorders, Scripps Research Institute, 10550 North Torrey Pines Road, SP30-2400, La Jolla, CA, 92037, USA,
出版信息
Psychopharmacology (Berl). 2014 Oct;231(19):3911-7. doi: 10.1007/s00213-014-3623-1. Epub 2014 Jun 13.
Abstract
摘要
相似文献
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Negative reinforcement via motivational withdrawal is the driving force behind the transition to addiction.通过动机撤回进行的负强化是成瘾转变背后的驱动力。
Psychopharmacology (Berl). 2014 Oct;231(19):3911-7. doi: 10.1007/s00213-014-3623-1. Epub 2014 Jun 13.
2
Is a 'general' theory of addiction possible? A commentary on: a multistep general theory of transition to addiction.是否可能存在一种成瘾的“通用”理论？对《成瘾转变的多步骤通用理论》的评论
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A general theory of transition to addiction it was and a general theory of transition to addiction it is: reply to the commentaries of Ahmed, Badiani, George & Koob, Kalivas & Gipson, and Tiffany.这曾是一个关于成瘾转变的一般理论，而现在它依然是：对艾哈迈德、巴迪亚尼、乔治和库布、卡利瓦斯和吉普森以及蒂芙尼的评论的回应。
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Consideration of a comprehensive animal model of addiction: the limitations of modeling a counterfeit condition.对成瘾综合动物模型的思考：模拟虚假状况的局限性。
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"Mourning" a lost opportunity.“哀悼”失去的机会。
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Antireward, compulsivity, and addiction: seminal contributions of Dr. Athina Markou to motivational dysregulation in addiction.抗奖赏、强迫性与成瘾：阿西娜·马尔库博士对成瘾中动机失调的开创性贡献。
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A redescription of data does not count as a general theory.对数据的重新描述不算作一个通用理论。
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A multistep general theory of transition to addiction.多步骤一般成瘾理论。
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Consolidating the Circuit Model for Addiction.巩固成瘾的回路模型。
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Kappa opioid receptor activation decreases inhibitory transmission and antagonizes alcohol effects in rat central amygdala.κ 阿片受体激活可减少大鼠杏仁中央核的抑制性传递，并拮抗酒精的作用。
Neuropharmacology. 2014 Feb;77:294-302. doi: 10.1016/j.neuropharm.2013.10.005. Epub 2013 Oct 21.
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Addict Biol. 2015 Jan;20(1):56-68. doi: 10.1111/adb.12077. Epub 2013 Jul 22.
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Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake.伏隔核去极化激活型 NMDAR 皮层激活介导了抵抗性酒精摄入。
Nat Neurosci. 2013 Aug;16(8):1094-100. doi: 10.1038/nn.3445. Epub 2013 Jun 30.
6
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