红细胞分布宽度（RDW）缺乏一致性。四种血液分析仪的评估。
Lack of harmonization of red blood cell distribution width (RDW). Evaluation of four hematological analyzers.
作者信息
Lippi Giuseppe, Pavesi Fernanda, Bardi Mirco, Pipitone Silvia
机构信息
Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Italy.
Laboratory of Clinical Chemistry and Hematology, Academic Hospital of Parma, Italy.
出版信息
Clin Biochem. 2014 Aug;47(12):1100-3. doi: 10.1016/j.clinbiochem.2014.06.003. Epub 2014 Jun 9.
OBJECTIVES
To assess analytical imprecision and comparability of red blood cell distribution width (RDW) on Abbott Sapphire, Mindray BC6800, Siemens Advia 2120 and Sysmex XE-5000.
DESIGN AND METHODS
Within-run imprecision was assessed on three pools and comparability using 132 inpatient samples.
RESULTS
The imprecision of RDW was comprised between 0.3 and 1.2%, but the values exhibited broad variation among different analyzers, with bias exceeding the desirable quality specifications.
CONCLUSIONS
Harmonization of RDW is still an unmet need.
目的
评估雅培 Sapphire、迈瑞 BC6800、西门子 Advia 2120 和希森美康 XE - 5000 上红细胞分布宽度（RDW）的分析不精密度和可比性。
设计与方法
在三个混合样本上评估批内不精密度，并使用 132 份住院患者样本评估可比性。
结果
RDW 的不精密度在 0.3%至 1.2%之间，但不同分析仪测得的值差异很大，偏差超出了理想的质量规范。
结论
RDW 的标准化仍是一项未满足的需求。
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