Nadjarzadeh Azadeh, Mehrsai Abdolrasoul, Mostafavi Ebrahim, Gohari Mahmood Reza, Shidfar Farzad
PhD., Assistant Professor, Nutritionist, Department of Nutrition, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
MD., Professor, Urologist, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2013 Nov;27(4):204-9.
Oxidative stress is detrimental to semen quality and has a significant role in the etiology of malesubfertility.
Dietary intake of antioxidants were compared between thirty two men with oligolastheno/ teratazoospermic(cases) and 32 normospermic volunteers (controls) attending fertility clinic in Mirza Koochak-khanHospital in Tehran, Iran. All participants were nonsmokers and matched according their age and Body MassIndex (BMI). Nutrient consumption was calculated using a semi- quantitative food frequency questionnaire.Semen samples were collected and were assessed by measuring volume, concentration, motility and morphology.
infertile subjects had a significantly lower intake of zinc and folate compare to control ones(p<0.001). Dietary intake of vitamin C and E was lower than recommended values in 59.4% of case group thatwas significantly different from control ones (p<0.05). In control group, 36.4 and 40.9% of participants had insufficientdietary intake of vitamin C and E, respectively. Significant correlations were found between folate(r=0.5, p<0.001), zinc (r=0.6, p<0.001) and percentage of motility and also between vitamin E and morphology(r=0.3, p=0.03), zinc and concentration (r=0.4, p=0.004) in all participants.
summary, a low intake of folate, zinc, and vitamin E were related to poor sperm concentrationand motility.
氧化应激对精液质量有害，在男性不育病因中起重要作用。
比较了伊朗德黑兰米尔扎·库恰克汗医院生育诊所的32名少弱畸精子症男性（病例组）和32名正常精子志愿者（对照组）的抗氧化剂饮食摄入量。所有参与者均不吸烟，并根据年龄和体重指数（BMI）进行匹配。使用半定量食物频率问卷计算营养素摄入量。收集精液样本，并通过测量体积、浓度、活力和形态进行评估。
与对照组相比，不育受试者的锌和叶酸摄入量显著较低（p<0.001）。病例组中59.4%的人维生素C和E的饮食摄入量低于推荐值，这与对照组有显著差异（p<0.05）。在对照组中，分别有36.4%和40.9%的参与者维生素C和E的饮食摄入量不足。在所有参与者中，叶酸（r=0.5，p<0.001）、锌（r=0.6，p<0.001）与活力百分比之间以及维生素E与形态（r=0.3，p=0.03）、锌与浓度（r=0.4，p=0.004）之间存在显著相关性。
总之，叶酸、锌和维生素E的低摄入量与精子浓度和活力差有关。
