通过活性阳离子聚合制备的基于聚磷腈的热响应性分子刷
Thermoresponsive Polyphosphazene-Based Molecular Brushes by Living Cationic Polymerization.
作者信息
Wilfert Sandra, Iturmendi Aitziber, Henke Helena, Brüggemann Oliver, Teasdale Ian
机构信息
Institute of Polymer Chemistry, Johannes Kepler University Linz, Welser Strasse 42, 4060 Leonding, Austria.
出版信息
Macromol Symp. 2014 Mar 1;337(1):116-123. doi: 10.1002/masy.201450314.
Abstract
A series of polyphosphazenes with molecular brush type structures have been prepared with controlled molecular weights and narrow polydispersities. The polymers show lower critical solution temperatures (LCST) between 18 and 90 °C, which can be easily tailored by choice of side-substituent to suit the required application. A temperature triggered self-assembly is observed to give stable colloidal aggregates with dimensions in the region of 100-300 nm.
摘要
一系列具有分子刷型结构的聚磷腈已被制备出来，其分子量可控且多分散性窄。这些聚合物的低临界溶液温度（LCST）在18至90℃之间，通过选择侧链取代基可以很容易地进行调整以适应所需的应用。观察到温度触发的自组装会产生尺寸在100 - 300nm范围内的稳定胶体聚集体。
相似文献
1
Thermoresponsive Polyphosphazene-Based Molecular Brushes by Living Cationic Polymerization.
Macromol Symp. 2014 Mar 1;337(1):116-123. doi: 10.1002/masy.201450314.
2
Branched Polyphosphazenes with Controlled Dimensions.
J Polym Sci A Polym Chem. 2013 Oct 1;51(20):4467-4473. doi: 10.1002/pola.26865.
3
Polyphosphazene Based Star-Branched and Dendritic Molecular Brushes.
Macromol Rapid Commun. 2016 May;37(9):769-74. doi: 10.1002/marc.201600057. Epub 2016 Mar 29.
4
Thermoresponsive Cationic Block Copolymer Brushes for Temperature-Modulated Stem Cell Separation.
Macromol Rapid Commun. 2020 Oct;41(19):e2000308. doi: 10.1002/marc.202000308. Epub 2020 Aug 17.
5
Monitoring Collapse of Uniform Cylindrical Brushes with a Thermoresponsive Corona in Water.
ACS Macro Lett. 2018 Feb 20;7(2):166-171. doi: 10.1021/acsmacrolett.7b00991. Epub 2018 Jan 10.
6
Water-Soluble, Biocompatible Polyphosphazenes with Controllable and pH-Promoted Degradation Behavior.
J Polym Sci A Polym Chem. 2014 Jan 15;52(2):287-294. doi: 10.1002/pola.27002.
7
Nonionic UCST-LCST Diblock Copolymers with Tunable Thermoresponsiveness Synthesized via PhotoRAFT Polymerization.
Macromol Rapid Commun. 2021 Apr;42(7):e2000648. doi: 10.1002/marc.202000648. Epub 2021 Jan 15.
8
Polyphosphazenes: Multifunctional, Biodegradable Vehicles for Drug and Gene Delivery.
Polymers (Basel). 2013 Mar 1;5(1):161-187. doi: 10.3390/polym5010161.
9
Surface and bulk collapse transitions of thermoresponsive polymer brushes.
Langmuir. 2010 Jan 19;26(2):838-47. doi: 10.1021/la902285t.
10
Effect of side group chemistry on the properties of biodegradable L-alanine cosubstituted polyphosphazenes.
Biomacromolecules. 2006 Mar;7(3):914-8. doi: 10.1021/bm050752r.
引用本文的文献
1
Injectable Thermoresponsive Hydrogels for Cancer Therapy: Challenges and Prospects.
Gels. 2023 May 16;9(5):418. doi: 10.3390/gels9050418.
2
Dual stimuli-responsive polyphosphazene-based molecular gates for controlled drug delivery in lung cancer cells.
RSC Adv. 2020 Jul 21;10(46):27305-27314. doi: 10.1039/d0ra03210g.
3
Reversible Speed Regulation of Self-Propelled Janus Micromotors via Thermoresponsive Bottle-Brush Polymers.
Chemistry. 2021 Feb 15;27(10):3262-3267. doi: 10.1002/chem.202004792. Epub 2021 Jan 12.
4
Main-Chain Phosphorus-Containing Polymers for Therapeutic Applications.
Molecules. 2020 Apr 8;25(7):1716. doi: 10.3390/molecules25071716.
5
Stimuli-Responsive Phosphorus-Based Polymers.
Eur J Inorg Chem. 2019 Mar 31;2019(11-12):1445-1456. doi: 10.1002/ejic.201801077. Epub 2018 Dec 10.
6
Water-Soluble, Biocompatible Polyphosphazenes with Controllable and pH-Promoted Degradation Behavior.
J Polym Sci A Polym Chem. 2014 Jan 15;52(2):287-294. doi: 10.1002/pola.27002.
7
Chain-end-functionalized polyphosphazenes via a one-pot phosphine-mediated living polymerization.
Macromol Rapid Commun. 2014 Jun;35(12):1135-41. doi: 10.1002/marc.201400114. Epub 2014 Apr 4.
本文引用的文献
1
Multi-responsive carboxymethyl polysaccharide crosslinked hydrogels containing Jeffamine side-chains.
Carbohydr Polym. 2012 Jun 20;89(2):578-85. doi: 10.1016/j.carbpol.2012.03.052. Epub 2012 Mar 28.
2
Polyphosphazenes: Multifunctional, Biodegradable Vehicles for Drug and Gene Delivery.
Polymers (Basel). 2013 Mar 1;5(1):161-187. doi: 10.3390/polym5010161.
3
Water-Soluble, Biocompatible Polyphosphazenes with Controllable and pH-Promoted Degradation Behavior.
J Polym Sci A Polym Chem. 2014 Jan 15;52(2):287-294. doi: 10.1002/pola.27002.
4
Branched Polyphosphazenes with Controlled Dimensions.
J Polym Sci A Polym Chem. 2013 Oct 1;51(20):4467-4473. doi: 10.1002/pola.26865.
5
Responsive biomimetic networks from polyisocyanopeptide hydrogels.
Nature. 2013 Jan 31;493(7434):651-5. doi: 10.1038/nature11839. Epub 2013 Jan 23.
6
A cooperative role for the counteranion in the PCl5-initiated living, cationic chain growth polycondensation of the phosphoranimine Cl3P═NSiMe3.
J Am Chem Soc. 2012 Sep 19;134(37):15293-6. doi: 10.1021/ja307703h. Epub 2012 Sep 5.
7
Thermoresponsive polymer colloids for drug delivery and cancer therapy.
Macromol Biosci. 2011 Dec 8;11(12):1722-34. doi: 10.1002/mabi.201100252. Epub 2011 Oct 19.
8
Pointed-oval-shaped micelles from crystalline-coil block copolymers by crystallization-driven living self-assembly.
Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8220-3. doi: 10.1002/anie.201003066.
9
Chemically crosslinkable thermosensitive polyphosphazene gels as injectable materials for biomedical applications.
Biomaterials. 2009 Oct;30(31):6178-92. doi: 10.1016/j.biomaterials.2009.08.015. Epub 2009 Aug 26.
10
Novel graft copolymers enhance in vitro delivery of antisense oligonucleotides in the presence of serum.
J Control Release. 2009 Dec 3;140(2):134-40. doi: 10.1016/j.jconrel.2009.08.008. Epub 2009 Aug 20.
Zotero 插件