Kopel Lianne S, Phipatanakul Wanda, Gaffin Jonathan M
Division of Respiratory Diseases, Boston Children's Hospital, Boston, MA.
Division of Allergy and Immunology, Boston Children's Hospital, Boston, MA; Division of Respiratory Epidemiology, Channing Laboratory, Brigham and Women's Hospital, Boston, MA.
Paediatr Respir Rev. 2014 Sep;15(3):256-62; quiz 262-3. doi: 10.1016/j.prrv.2014.04.017. Epub 2014 May 16.
This review discusses various aspects of social disadvantage and their association with poor asthma control, including socioeconomic status, exposure to psychosocial stress and violence, minority affiliation, environmental concerns such as allergens and pollution, and poverty in rural settings. Each of these elements has been linked with worsened asthma outcomes in children. Known and hypothesized mechanisms behind these associations are described in an effort to further understand the complex entity of poorly controlled asthma among socially deprived children. Intervention studies to improve asthma outcomes in these vulnerable populations are also described.
本综述讨论了社会劣势的各个方面及其与哮喘控制不佳的关联,包括社会经济地位、接触心理社会压力和暴力、少数群体归属、诸如过敏原和污染等环境问题,以及农村地区的贫困状况。这些因素中的每一个都与儿童哮喘病情恶化有关。文中描述了这些关联背后已知和假设的机制,以进一步了解社会弱势儿童中哮喘控制不佳这一复杂情况。还介绍了改善这些弱势群体哮喘治疗效果的干预研究。