Department of Neurology, Vanderbilt University Medical Center, 1161 21st Avenue South, A-0118 Medical Center North, Nashville, TN, 37232, USA,
Curr Treat Options Neurol. 2014 Aug;16(8):304. doi: 10.1007/s11940-014-0304-7.
Sleep disorders are among the most common non-motor symptoms in Parkinson's Disease (PD). In some cases, symptoms can precede a diagnosis of PD by many years, but otherwise they are commonly encountered during the clinical care of patients. Unfortunately, sleep problems are under-recognized and subsequently inadequately addressed. In our experience, when properly addressed, physicians and patients are quickly aware of the often-debilitating nature of sleep dysfunction. This does not mean that solutions are easily attainable. Sleep in PD is held in a delicate balance, influenced by the disease process, medications, co-morbid symptoms, and a variety of other factors. For this reason, management of sleep in PD often requires an inter-disciplinary approach. Physicians should have an intimate knowledge of the many sleep problems apparent in PD, as well as appreciate the challenge presented by diverse therapeutic options that can both ameliorate and aggravate symptoms.
睡眠障碍是帕金森病（PD）中最常见的非运动症状之一。在某些情况下，这些症状可能在 PD 诊断前多年就出现了，但在患者的临床护理中通常会遇到。不幸的是，睡眠问题未得到充分认识，因此也未得到充分解决。根据我们的经验，当得到妥善处理时，医生和患者很快就会意识到睡眠功能障碍常常具有使人衰弱的性质。这并不意味着解决方案很容易实现。PD 中的睡眠处于微妙的平衡之中，受疾病进程、药物、合并症状和各种其他因素的影响。因此，PD 中的睡眠管理通常需要跨学科的方法。医生应该非常了解 PD 中明显存在的许多睡眠问题，并认识到各种治疗选择所带来的挑战，这些选择既能改善症状，也能加重症状。
