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本文引用的文献

1
Periodontal regeneration following implantation of cementum and periodontal ligament-derived cells.牙周膜细胞和牙骨质来源细胞植入后的牙周再生。
J Periodontal Res. 2012 Feb;47(1):33-44. doi: 10.1111/j.1600-0765.2011.01402.x. Epub 2011 Sep 12.
2
Bioengineered periodontal tissue formed on titanium dental implants.钛种植体上形成的生物工程牙周组织。
J Dent Res. 2011 Feb;90(2):251-6. doi: 10.1177/0022034510384872. Epub 2010 Dec 13.
3
Tissue-engineered ligament: implant constructs for tooth replacement.组织工程化韧带:用于牙齿替代的植入物构建体。
J Clin Periodontol. 2010 Aug 1;37(8):750-8. doi: 10.1111/j.1600-051X.2010.01588.x. Epub 2010 Jun 9.
4
Getting to the root of dental implant tissue engineering.探寻牙种植体组织工程的根源。
J Clin Periodontol. 2010 Aug 1;37(8):747-9. doi: 10.1111/j.1600-051X.2010.01589.x. Epub 2010 Jun 9.
5
Biomimetic hybrid scaffolds for engineering human tooth-ligament interfaces.仿生杂交支架用于工程化人牙-韧带界面。
Biomaterials. 2010 Aug;31(23):5945-52. doi: 10.1016/j.biomaterials.2010.04.027. Epub 2010 May 14.
6
Future approaches in periodontal regeneration: gene therapy, stem cells, and RNA interference.牙周再生的未来方法:基因治疗、干细胞和RNA干扰。
Dent Clin North Am. 2010 Jan;54(1):141-55. doi: 10.1016/j.cden.2009.09.002.
7
Ultrastructure of the interface between periodontal tissues and titanium mini-implants.牙周组织与钛微种植体界面的超微结构。
Angle Orthod. 2010 May;80(3):459-65. doi: 10.2319/032509-177.1.
8
Cell sheet engineering and other novel cell-based approaches to periodontal regeneration.细胞片工程及其他基于细胞的牙周再生新方法。
Periodontol 2000. 2009;51:220-38. doi: 10.1111/j.1600-0757.2009.00312.x.
9
Tooth-implant connection: a bibliographic review.牙种植体连接:文献综述。
Med Oral Patol Oral Cir Bucal. 2010 Mar 1;15(2):e387-94. doi: 10.4317/medoral.15.e387.
10
Experimental formation of periodontal structure around titanium implants utilizing bone marrow mesenchymal stem cells: a pilot study.利用骨髓间充质干细胞在钛种植体周围实验性形成牙周结构:一项初步研究。
J Oral Implantol. 2009;35(3):106-29. doi: 10.1563/1548-1336-35.3.106.

牙周整合种植体:一个革命性的概念。

Periodontio-integrated implants: A revolutionary concept.

作者信息

Gulati Minkle, Anand Vishal, Govila Vivek, Jain Nikil, Rastogi Pavitra, Bahuguna Rohit, Anand Bhargavi

机构信息

Department of Periodontics, Babu Banarasi Das College of Dental Sciences, Babu Banarasi Das University, Lucknow, Uttar Pradesh, India.

Department of Periodontics, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Dent Res J (Isfahan). 2014 Mar;11(2):154-62.

PMID:24932184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4052639/
Abstract

Though the fields of regenerative dentistry and tissue engineering have undergone significant advancements, yet its application to the field of implant-dentistry is lacking; in the sense that presently the implants are being placed with the aim of attaining osseointegration without giving consideration to the regeneration of periodontium around the implant. The following article reveals the clinical benefits of such periodontio-integrated implants and reviews the relevant scientific proofs. A comprehensive research to provide scientific evidence supporting the feasibility of periodontio-integrated implants was carried out using various online resources such as PubMed, Wiley-Blackwell, Elsevier etc., to retrieve studies published between 1980 and 2012 using the following key words: "implant," "tissue engineering," "periodontium," "osseo-integration," "osseoperception," "regeneration" (and their synonyms) and it was found that in the past three decades, several successful experiments have been conducted to devise "implant supported by the periodontium"that can maintain form, function and potential proprioceptive responses similar to a natural tooth. Based on these staunch evidences, the possibility of the future clinical use of such implant can be strongly stated which would revolutionize the implant dentistry and will be favored by the patients as well. However, further studies are required to validate the same.

摘要

尽管再生牙科和组织工程领域已取得显著进展,但其在种植牙科领域的应用仍很欠缺;目前种植体植入的目的是实现骨整合,而未考虑种植体周围牙周组织的再生。以下文章揭示了这种牙周整合种植体的临床益处,并回顾了相关科学证据。利用各种在线资源,如PubMed、Wiley-Blackwell、Elsevier等,进行了一项全面研究,以提供支持牙周整合种植体可行性的科学证据,使用以下关键词检索1980年至2012年间发表的研究:“种植体”、“组织工程”、“牙周组织”、“骨整合”、“骨感知”、“再生”(及其同义词),结果发现,在过去三十年里,已经进行了几项成功的实验,设计出“由牙周组织支持的种植体”,其能够保持与天然牙相似的形态、功能和潜在本体感觉反应。基于这些确凿证据,可以有力地说明这种种植体未来临床应用的可能性,这将给种植牙科带来变革,也会受到患者的青睐。然而,还需要进一步研究来验证这一点。