Laboratorio de Parasitología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autónoma de Yucatán, Mérida, Yucatán, México; School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana
Laboratorio de Parasitología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi," Universidad Autónoma de Yucatán, Mérida, Yucatán, México; School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana.
Am J Trop Med Hyg. 2014 Aug;91(2):348-53. doi: 10.4269/ajtmh.13-0527. Epub 2014 Jun 16.
Our objective was to determine the seroprevalence of Trypanosoma cruzi infection among mothers and children in two rural Mayan communities in Yucatan, Mexico and examine sociodemographic characteristics and adverse reproductive outcomes associated with maternal infection. We performed household surveys in the communities of Sudzal and Teya. Mothers were interviewed, and blood samples were obtained to perform rapid tests and enzyme-linked immunosorbent assays (ELISAs). We surveyed 390 mothers and 685 children. The overall seroprevalence was 2.3% among mothers and 0.4% among children. In Sudzal, we found a seroprevalence of 4.4% among mothers and 0.7% in children. In Teya, we found a seroprevalence of 0.9% among mothers and 0.3% among children. Compared with uninfected mothers, seropositive mothers reported more stillbirths (relative risk = 4.7; 95% confidence interval = 2.1-10.4). T. cruzi infection is present in these communities, and infected children indicate active transmission. Seropositivity in mothers is associated with a history of adverse reproductive outcomes.
我们的目的是确定在墨西哥尤卡坦的两个农村玛雅社区中母亲和儿童中克氏锥虫感染的血清流行率，并检查与母体感染相关的社会人口统计学特征和不良生殖结局。我们在 Sudzal 和 Teya 社区进行了家庭调查。对母亲进行了访谈，并采集了血液样本进行快速检测和酶联免疫吸附测定（ELISA）。我们调查了 390 名母亲和 685 名儿童。母亲的总体血清阳性率为 2.3%，儿童为 0.4%。在 Sudzal，我们发现母亲的血清阳性率为 4.4%，儿童为 0.7%。在 Teya，我们发现母亲的血清阳性率为 0.9%，儿童为 0.3%。与未感染的母亲相比，血清阳性的母亲报告的死产更多（相对风险=4.7；95%置信区间=2.1-10.4）。这些社区存在克氏锥虫感染，感染的儿童表明存在活跃的传播。母亲的血清阳性与不良生殖结局的病史有关。
