群居水螅虫类共生长腕水螅（Hydractinia symbiolongicarpus）中多态和单态游动孢子所潜在的基因共表达模块。
Gene co-expression modules underlying polymorphic and monomorphic zooids in the colonial hydrozoan, Hydractinia symbiolongicarpus.
作者信息
Plachetzki David C, Sabrina Pankey M, Johnson Brian R, Ronne Eric J, Kopp Artyom, Grosberg Richard K
机构信息
*Department of Molecular, Cellular and Biomedical Sciences, The University of New Hampshire, Durham, NH 03801, USA; Department of Ecology Evolution and Marine Biology, The University of California at Santa Barbara, Santa Barbara, CA 93106, USA; Department of Entomology, The University of California at Davis, Davis, CA 95616, USA; Department of Evolution and Ecology, Center for Population Biology, The University of California at Davis, Davis, CA 95616, USA
*Department of Molecular, Cellular and Biomedical Sciences, The University of New Hampshire, Durham, NH 03801, USA; Department of Ecology Evolution and Marine Biology, The University of California at Santa Barbara, Santa Barbara, CA 93106, USA; Department of Entomology, The University of California at Davis, Davis, CA 95616, USA; Department of Evolution and Ecology, Center for Population Biology, The University of California at Davis, Davis, CA 95616, USA.
出版信息
Integr Comp Biol. 2014 Jul;54(2):276-83. doi: 10.1093/icb/icu080. Epub 2014 Jun 15.
Advances in sequencing technology have forced a quantitative revolution in Evolutionary Biology. One important feature of this renaissance is that comprehensive genomic resources can be obtained quickly for almost any taxon, thus speeding the development of new model organisms. Here, we analyze 20 RNA-seq libraries from morphologically, sexually, and genetically distinct polyp types from the gonochoristic colonial hydrozoan, Hydractinia symbiolongicarpus (Cnidaria). Analyses of these data using weighted gene co-expression networks highlight deeply conserved genetic elements of animal spermatogenesis and demonstrate the utility of these methods in identifying modules of genes that correlate with different zooid types across various statistical contrasts. RNA-seq data and analytical scripts described here are deposited in publicly available databases.
测序技术的进步推动了进化生物学的定量革命。这场复兴的一个重要特征是，几乎可以快速为任何分类单元获取全面的基因组资源，从而加速了新型模式生物的开发。在这里，我们分析了来自雌雄异体的群体水螅虫（Hydractinia symbiolongicarpus，刺胞动物门）形态、性别和遗传上不同的息肉类型的20个RNA测序文库。使用加权基因共表达网络对这些数据进行分析，突出了动物精子发生中深度保守的遗传元件，并证明了这些方法在识别与不同统计对比中不同类螅体类型相关的基因模块方面的效用。这里描述的RNA测序数据和分析脚本已存入公开可用的数据库。
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