Department of Ophthalmology, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Naka-ku Hamamatsu, Hamamatsu, Japan.
Seirei Christopher University, Shizuoka, Japan.
Sci Rep. 2024 Oct 10;14(1):23703. doi: 10.1038/s41598-024-69140-w.
The effects of meteorological conditions on IOP using a large-scale health examination cohort were investigated. There were a total of 811,854 measurements from 126,630 eyes of 63,839 subjects in 9 years from a health checkup cohort followed up annually for age, sex, body height, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), and IOP. The effects of these variables and the meteorological data of daily average temperature (TP), daily average local atmospheric pressure (AP), daily average volumetric humidity (VH), and daily amount of rainfall (RF) on the day of IOP measurement on IOP were investigated. Several variables were significantly associated with IOP, including sex, age, body height, BMI, SBP, DBP, average TP, average AP, average VH, RF, white blood cell count, red blood cell count, hemoglobin, aspartate aminotransferase, alanine aminotransferase, guanosine triphosphate, calcium, and HbA1c. This study indicated a correlation between meteorological factors and IOP. Higher AP and RF were associated with elevated IOP, whereas higher TP and VH were associated with decreased IOP.
本研究利用大规模健康体检队列调查了气象条件对眼压（IOP）的影响。该研究纳入了 9 年期间定期随访的健康体检队列中的 63839 名受试者的 126630 只眼共 811854 次测量值，这些受试者的年龄、性别、身高、体质量指数（BMI）、收缩压（SBP）、舒张压（DBP）和 IOP 等信息均完整。本研究分析了这些变量以及每日平均温度（TP）、平均局部大气压（AP）、平均容积湿度（VH）和日降雨量（RF）等气象数据与当日 IOP 测量值之间的相关性。结果发现，性别、年龄、身高、BMI、SBP、DBP、平均 TP、平均 AP、平均 VH、RF、白细胞计数、红细胞计数、血红蛋白、天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、三磷酸鸟苷、钙和 HbA1c 等多个变量与 IOP 显著相关。本研究表明气象因素与 IOP 之间存在相关性，AP 和 RF 较高与 IOP 升高相关，而 TP 和 VH 较高与 IOP 降低相关。
