Asotic Amir, Taric Suada, Asotic Jasmina
Med Arch. 2014;68(2):106-9. doi: 10.5455/medarh.2014.68.106-109.
In endeavor to suppress the cervical carcinoma there are several possible approaches including measures of primary and secondary prevention. So far effects of these measures on the number of cases and mortality rate of cervical carcinoma were modest. Only exception is organized testing based on cytological exam of the cervical smear - Pap test, which has proven to be highly effective in reducing the number of cases and mortality of cervical carcinoma in countries with this program. Goal of this research is analysis of correlation between abnormal cytological test results and pathohistological diagnosis of all patients in the analyzed period.
Research is descriptive, analytical, comparative, and partly epidemiological. Results of cytological and pathohistological diagnostic in the period between January 1, 2009 and December 31, 2011 were used for analysis. All analyzed patients had colposcopy exam and Pap test, and patients with abnormal results of this test underwent cervical biopsy for pathohistological diagnostics.
We came to following results and conclusions: total number of L-SIL and H-SIL (PAPA III) results was 395 (6.20%) in comparison to total sample of 5894 (92.44%) patients. There is a statistically significant difference in relation to PHD result of cervical biopsy after L1-SIL and H-SIL (PAPA II and IV), and highest statistical margin is in relation of CIN II changes to cytological findings, issued at Clinic of Obstetrics and Gynecology and other health institutions. We come to conclusion that the highest percentage of patients with L-SIL and H-SIL findings is in age group between 0-29 years old. Statistical analysis has shown a positive trend in number of younger patients with L-SIL and H-SIL (PAPA III and IV), with average age of patients in 2011 being 31.12 +/- 9.12 years old.
为了抑制宫颈癌，有几种可能的方法，包括一级和二级预防措施。到目前为止，这些措施对宫颈癌的病例数和死亡率的影响不大。唯一的例外是基于宫颈涂片细胞学检查（巴氏试验）的有组织检测，在实施该计划的国家，这已被证明在减少宫颈癌病例数和死亡率方面非常有效。本研究的目的是分析分析期内所有患者的细胞学检查异常结果与病理组织学诊断之间的相关性。
本研究具有描述性、分析性、比较性且部分为流行病学研究。分析采用2009年1月1日至2011年12月31日期间的细胞学和病理组织学诊断结果。所有分析的患者均接受了阴道镜检查和巴氏试验，该试验结果异常的患者接受了宫颈活检以进行病理组织学诊断。
我们得出了以下结果和结论：与5894例（92.44%）患者的总样本相比，低度鳞状上皮内病变（L-SIL）和高度鳞状上皮内病变（H-SIL，巴氏III级）结果的总数为395例（6.20%）。L1-SIL和H-SIL（巴氏II级和IV级）后宫颈活检的病理组织学诊断结果存在统计学显著差异，在妇产科诊所和其他医疗机构，CIN II级变化与细胞学检查结果的统计学差异最大。我们得出结论，L-SIL和H-SIL检查结果的患者中，最高比例出现在0至29岁年龄组。统计分析显示，L-SIL和H-SIL（巴氏III级和IV级）的年轻患者数量呈上升趋势，2011年患者的平均年龄为31.12 +/- 9.12岁。
