Bal Dhruti, Nagesh Karthik, Surendra H S, Chiradoni Deepak, Gomathy G
Britannia Industries Limited, Research and Development, Britannia Gardens, Old Airport Road, Bangalore, 560017, India,
Indian J Pediatr. 2015 Mar;82(3):253-9. doi: 10.1007/s12098-014-1483-7. Epub 2014 Jun 20.
To assess the efficacy of iron fortified biscuits, in high and low dosages, on the hemoglobin levels of anemic school going children aged 6 to 12 y.
The nutrition intervention was conducted in primary schools located in villages at Shimoga district, Karnataka. School children aged 6 to 12 y who were anemic, with hemoglobin level <11.5 g/dl were considered for the nutrition intervention. The sampling design undertaken was quasi experimental with pre and post stages of outcome. The children enrolled were divided into two groups. One group received high dosage of iron fortified biscuits (30 mg of elemental iron/6 biscuits) and the second group received a relatively lower dosage of iron fortified biscuits (1.8 mg of elemental iron/6 biscuits) for a period of 120 d. The hemoglobin levels were estimated pre and post fortified biscuit supplementation by cyanomethemoglobin method.
There was an increase in the mean hemoglobin level of children which was found to be higher in group I (high iron fortified biscuits) (1.06 g/dl) compared to group II (low iron fortified biscuits) (0.41 g/dl), significant at 0.01 level (t = 3.84**).
In the current nutrition intervention, both high and low iron fortified biscuits led to a significant enhancement in the body weight and hemoglobin status of anemic school children in a rural setup. The nutrition intervention clearly highlights biscuits as an ideal fortification vehicle for addressing anemia.
评估高剂量和低剂量的铁强化饼干对6至12岁贫血学童血红蛋白水平的疗效。
在卡纳塔克邦希莫加区农村的小学开展营养干预。将血红蛋白水平<11.5 g/dl的6至12岁贫血学童纳入营养干预。采用的抽样设计为准实验性，有结果的前后阶段。将入组儿童分为两组。一组接受高剂量铁强化饼干（30毫克元素铁/6块饼干），第二组接受相对低剂量的铁强化饼干（1.8毫克元素铁/6块饼干），为期120天。通过氰化高铁血红蛋白法在补充强化饼干前后估计血红蛋白水平。
儿童的平均血红蛋白水平有所升高，发现第一组（高铁强化饼干）（1.06 g/dl）高于第二组（低铁强化饼干）（0.41 g/dl），在0.01水平上具有显著性（t = 3.84**）。
在当前的营养干预中，高剂量和低剂量的铁强化饼干均使农村地区贫血学童的体重和血红蛋白状况得到显著改善。该营养干预明确表明饼干是解决贫血问题的理想强化载体。
