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向心性汗孔角化症:汗孔角化症的一种罕见变异型。

Porokeratosis ptychotropica: a rare variant of porokeratosis.

作者信息

D'souza Paschal, Dhali Tapan Kumar, Arora Shikha, Gupta Himanshu, Khanna Urmi

机构信息

Department of Dermatology, ESI- PGIMSR, Basaidarapur, New Delhi, India.

出版信息

Dermatol Online J. 2014 Jun 15;20(6):13030/qt26d5p9v7.

PMID:24945649
Abstract

BACKGROUND

Porokeratosis, a well recognized disorder of keratinization, is known to have several clinical variants. This report describes a rare variant characterized by verrucous plaques.

METHODS

An adult male presented with a slowly progressive verrucous plaque on the gluteal region that was resistant to conventional therapy. Careful inspection revealed a keratotic ridge at the plaque border leading to the diagnosis.

RESULTS

Histopathology showed the presence of multiple cornoid lamellae confirming the diagnosis of porokeratosis ptychotropica.

CONCLUSIONS

Porokeratosis ptychotropica is a rare variant of porokeratosis with fewer than 25 cases described in the literature. This report is to highlight the importance of considering this particular entity in the diagnosis of genitogluteal plaques, especially those not responding to conventional modalities.

摘要

背景

汗孔角化症是一种公认的角化异常疾病,已知有多种临床变体。本报告描述了一种以疣状斑块为特征的罕见变体。

方法

一名成年男性臀部出现缓慢进展的疣状斑块,对传统治疗耐药。仔细检查发现斑块边界有角质化嵴,从而得出诊断。

结果

组织病理学显示存在多个鸡眼样板层,证实为褶烂性汗孔角化症的诊断。

结论

褶烂性汗孔角化症是汗孔角化症的一种罕见变体,文献中报道的病例少于25例。本报告旨在强调在诊断臀生殖器斑块时考虑这一特殊实体的重要性,尤其是那些对传统治疗无反应的斑块。

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1
Porokeratosis ptychotropica: a rare variant of porokeratosis.向心性汗孔角化症:汗孔角化症的一种罕见变异型。
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Verrucous porokeratosis of the gluteal cleft (porokeratosis ptychotropica): a rare disorder easily misdiagnosed.臀沟疣状汗孔角化症(向褶性汗孔角化症):一种易被误诊的罕见病症。
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引用本文的文献

1
Porokeratoses-A Comprehensive Review on the Genetics and Metabolomics, Imaging Methods and Management of Common Clinical Variants.汗孔角化症——关于常见临床变异型的遗传学、代谢组学、成像方法及管理的综合综述
Metabolites. 2023 Nov 26;13(12):1176. doi: 10.3390/metabo13121176.
2
Porokeratosis Ptychotropica: Dermoscopy, Reflectance Confocal Microscopy, and Histopathological Correlation.趋肤性汗孔角化症:皮肤镜、反射式共聚焦显微镜检查及组织病理学相关性研究
Indian J Dermatol. 2021 Sep-Oct;66(5):540-542. doi: 10.4103/ijd.ijd_894_20.
3
Genitogluteal porokeratosis: a clinical review.
生殖臀区汗孔角化症:临床综述
Clin Cosmet Investig Dermatol. 2018 May 1;11:219-229. doi: 10.2147/CCID.S143085. eCollection 2018.
4
Porokeratosis ptychotropica.趋皮性汗孔角化症
An Bras Dermatol. 2016 Sep-Oct;91(5 suppl 1):134-136. doi: 10.1590/abd1806-4841.20164399.
5
[Verrucous variant of porokeratosis of Mibelli as a differential diagnosis of psoriasis vulgaris].[米贝利汗孔角化症的疣状变体作为寻常型银屑病的鉴别诊断]
Hautarzt. 2016 Mar;67(3):244-8. doi: 10.1007/s00105-015-3720-z.