内源性定向时的优势反应。

Overt responses during covert orienting.

机构信息

Departments of Physiology & Pharmacology, Psychology, Robarts Research Institute, University of Western Ontario, London, ON N6A 5B7, Canada.

Centre for Neuroscience Studies, Departments of Biomedical and Molecular Sciences, Psychology, Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.

出版信息

Neuron. 2014 Jun 18;82(6):1230-43. doi: 10.1016/j.neuron.2014.05.040.

DOI:10.1016/j.neuron.2014.05.040

PMID:24945769

Abstract

A distributed network of cortical and subcortical brain areas controls our oculomotor behavior. This network includes the superior colliculus (SC), which coordinates an ancient visual grasp reflex via outputs that ramify widely within the brainstem and spinal cord, accessing saccadic and other premotor and autonomic circuits. In this Review, we discuss recent results correlating subliminal SC activity in the absence of saccades with diverse components of the visual grasp reflex, including neck and limb muscle recruitment, pupil dilation, and microsaccade propensity. Such subtle manifestations of covert orienting are accessible in the motor periphery and may provide the next generation of oculomotor biomarkers in health and disease.

摘要

大脑皮质和皮质下区域的分布式网络控制着我们的眼球运动行为。这个网络包括上丘（SC），它通过广泛分支到脑干和脊髓中的输出来协调古老的视觉抓握反射，从而访问扫视和其他运动前和自主神经回路。在这篇综述中，我们讨论了最近的结果，这些结果将无扫视情况下的潜意识 SC 活动与视觉抓握反射的不同成分相关联，包括颈部和肢体肌肉募集、瞳孔扩张和微扫视倾向。这种隐蔽定向的微妙表现可以在运动外围中获得，并且可能为健康和疾病中的下一代眼球运动生物标志物提供依据。