Kassebaum N J, Bernabé E, Dahiya M, Bhandari B, Murray C J L, Marcenes W
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA Department of Anesthesiology and Pain Medicine, University of Washington and Seattle Children's Hospital, Seattle, WA, USA.
Division of Population and Patient Health, King's College London, Dental Institute at Guy's, King's College, and St. Thomas' Hospitals, London, UK.
J Dent Res. 2014 Jul;93(7 Suppl):20S-28S. doi: 10.1177/0022034514537828.
The goal of the Global Burden of Disease 2010 Study has been to systematically produce comparable estimates of the burden of 291 diseases and injuries and their associated 1,160 sequelae from 1990 to 2010. We aimed to report here internally consistent prevalence and incidence estimates of severe tooth loss for all countries, 20 age groups, and both sexes for 1990 and 2010. The systematic search of the literature yielded 5,618 unique citations. After titles and abstracts were screened, 5,285 citations were excluded as clearly not relevant to this systematic review, leaving 333 for full-text review; 265 publications were further excluded following the validity assessment. A total of 68 studies-including 285,746 individuals aged 12 yr or older in 26 countries-were included in the meta-analysis using modeling resources of the Global Burden of Disease 2010 Study. Between 1990 and 2010, the global age-standardized prevalence of edentate people decreased from 4.4% (95% uncertainty interval: 4.1%, 4.8%) to 2.4% (95% UI: 2.2%, 2.7%), and incidence rate decreased from 374 cases per 100,000 person-years (95% UI: 347, 406) to 205 cases (95% UI: 187, 226). No differences were found by sex in 2010. Prevalence increased gradually with age, showing a steep increase around the seventh decade of life that was associated with a peak in incidence at 65 years. Geographic differences in prevalence, incidence, and rate of improvement from 1990 to 2010 were stark. Our review of available quality literature on the epidemiology of tooth loss shows a significant decline in the prevalence and incidence of severe tooth loss between 1990 and 2010 at the global, regional, and country levels.
《2010年全球疾病负担研究》的目标是系统地得出1990年至2010年期间291种疾病和损伤及其相关的1160种后遗症负担的可比估计值。我们旨在在此报告1990年和2010年所有国家、20个年龄组以及男女的严重牙齿缺失的内部一致的患病率和发病率估计值。对文献的系统检索产生了5618条独特的引文。在筛选标题和摘要后，5285条引文因明显与本系统评价无关而被排除，剩下333条进行全文审查；在有效性评估后，又排除了265篇出版物。使用《2010年全球疾病负担研究》的建模资源，共有68项研究（包括26个国家的285746名12岁及以上个体）被纳入荟萃分析。1990年至2010年期间，全球无牙者的年龄标准化患病率从4.4%（95%不确定区间：4.1%，4.8%）降至2.4%（95%不确定区间：2.2%，2.7%），发病率从每10万人年374例（95%不确定区间：347，406）降至205例（95%不确定区间：187，226）。2010年按性别未发现差异。患病率随年龄逐渐增加，在生命的第七个十年左右急剧上升，这与65岁时的发病率峰值相关。1990年至2010年期间，患病率、发病率和改善率的地理差异明显。我们对现有关于牙齿缺失流行病学的高质量文献的综述表明，1990年至2010年期间，全球、区域和国家层面严重牙齿缺失的患病率和发病率显著下降。
