急性病毒性肝炎：病因与演变
Acute viral hepatitis: aetiology and evolution.
作者信息
Chow C B, Lau T T, Leung N K, Chang W K
机构信息
Paediatric A Unit, Princess Margaret Hospital, Hong Kong.
出版信息
Arch Dis Child. 1989 Feb;64(2):211-3. doi: 10.1136/adc.64.2.211.
Over a period of three and a half years, 348 consecutive children with acute hepatitis were studied. There were 205 boys and 143 girls aged from 3 months to 12 years old. The most common type was hepatitis A, of which there were 281 cases, 81% of the total; there were 41 in the under 4 years old age group (63% of that group), 99 in the 5-8 year old age group (87% of that group) and 141 in the 8-12 year old age group (83% of that group). Hepatitis B occurred in 29 (8% of the total), and non-A, non-B hepatitis occurred in 35 (10%). All the children with hepatitis A and all but one with hepatitis B recovered. There were three deaths from fulminant hepatitis, one in the group with hepatitis B and two with non-A, non-B. Clearance of the hepatitis B surface antigen was fast, by six months 26 patients having cleared the antigen and 21 (77%) being positive for hepatitis B surface antibody. One patient became a carrier of hepatitis B surface antigen.
在三年半的时间里，对348名连续的急性肝炎患儿进行了研究。其中有205名男孩和143名女孩，年龄从3个月到12岁。最常见的类型是甲型肝炎，共281例，占总数的81%；4岁以下年龄组有41例（占该组的63%），5至8岁年龄组有99例（占该组的87%），8至12岁年龄组有141例（占该组的83%）。乙型肝炎有29例（占总数的8%），非甲非乙型肝炎有35例（占10%）。所有甲型肝炎患儿以及除1例之外的所有乙型肝炎患儿均康复。有3例因暴发性肝炎死亡，1例为乙型肝炎组，2例为非甲非乙型肝炎组。乙型肝炎表面抗原清除迅速，到6个月时，26例患者已清除抗原，21例（77%）乙型肝炎表面抗体呈阳性。1例患者成为乙型肝炎表面抗原携带者。
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