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Pathogenesis of irritable bowel syndrome: is it really in the gene?

作者信息

Ghoshal Uday C, Singh Rajan

机构信息

Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

J Neurogastroenterol Motil. 2014 Jul 31;20(3):284-6. doi: 10.5056/jnm14071.

DOI:10.5056/jnm14071
PMID:24953715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4102161/
Abstract
摘要

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J Neurogastroenterol Motil. 2014 Jul 31;20(3):388-99. doi: 10.5056/jnm14020.
2
No association of G-protein beta polypeptide 3 polymorphism with irritable bowel syndrome: evidence from a meta-analysis.G蛋白β多肽3基因多态性与肠易激综合征无关联:一项荟萃分析的证据
World J Gastroenterol. 2014 May 28;20(20):6345-52. doi: 10.3748/wjg.v20.i20.6345.
3
Irritable bowel syndrome: emerging paradigm in pathophysiology.肠易激综合征:病理生理学中的新兴范式
World J Gastroenterol. 2014 Mar 14;20(10):2456-69. doi: 10.3748/wjg.v20.i10.2456.
4
The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies.血清素转运体基因多态性(5-HTTLPR)与肠易激综合征:25项研究的荟萃分析
BMC Gastroenterol. 2014 Feb 10;14:23. doi: 10.1186/1471-230X-14-23.
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Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome.中国肠易激综合征患者中1型大麻素受体与脂肪酸酰胺水解酶基因多态性的关联
J Gastroenterol Hepatol. 2014 Jun;29(6):1186-91. doi: 10.1111/jgh.12513.
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Cytokine gene polymorphisms are associated with irritable bowel syndrome: a systematic review and meta-analysis.细胞因子基因多态性与肠易激综合征相关:系统评价和荟萃分析。
Neurogastroenterol Motil. 2012 Dec;24(12):1102-e566. doi: 10.1111/j.1365-2982.2012.01990.x. Epub 2012 Aug 16.
7
Is There Enough Evidence for the Association of GNβ3 C825T Polymorphism With Functional Dyspepsia and Irritable Bowel Syndrome?关于GNβ3 C825T基因多态性与功能性消化不良及肠易激综合征之间的关联,是否有足够的证据?
J Neurogastroenterol Motil. 2012 Jul;18(3):348-9. doi: 10.5056/jnm.2012.18.3.348. Epub 2012 Jul 10.
8
Polymorphisms of the Serotonin Transporter Gene and G-Protein β3 Subunit Gene in Korean Children with Irritable Bowel Syndrome and Functional Dyspepsia.韩国肠易激综合征和功能性消化不良儿童的 5-羟色胺转运体基因和 G 蛋白β3 亚单位基因多态性。
Gut Liver. 2012 Apr;6(2):223-8. doi: 10.5009/gnl.2012.6.2.223. Epub 2012 Apr 17.
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Serotonin transporter gene (SLC6A4) polymorphism in patients with irritable bowel syndrome and healthy controls.肠易激综合征患者和健康对照者的 5-羟色胺转运体基因(SLC6A4)多态性。
J Gastrointestin Liver Dis. 2012 Mar;21(1):31-8.
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Gene, environment, and brain-gut interactions in irritable bowel syndrome.肠易激综合征中的基因、环境和脑肠相互作用。
J Gastroenterol Hepatol. 2011 Apr;26 Suppl 3:110-5. doi: 10.1111/j.1440-1746.2011.06631.x.