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用于治疗递送的无机纳米颗粒:试验、困境与前景。

Inorganic Nanoparticles for Therapeutic Delivery: Trials, Tribulations and Promise.

作者信息

Tonga Gulen Yesilbag, Moyano Daniel F, Kim Chang Soo, Rotello Vincent M

机构信息

Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant Street, Amherst, MA, 01003, USA.

出版信息

Curr Opin Colloid Interface Sci. 2014 Apr 1;19(2):49-55. doi: 10.1016/j.cocis.2014.03.004.

Abstract

Inorganic nanomaterials have a wide array of physical and structural properties that make them attractive candidates for imaging and therapeutic delivery. Nanoparticle platforms have been intensely studied for these applications, and examples are starting to enter the clinic. This review looks at why inorganic particles provide promising platforms for biomedicine, and what issues need to be addressed for them to reach their potential.

摘要

无机纳米材料具有广泛的物理和结构特性,这使其成为成像和治疗递送方面颇具吸引力的候选材料。纳米颗粒平台已针对这些应用展开了深入研究,并且一些实例已开始进入临床阶段。本综述探讨了为何无机颗粒为生物医学提供了有前景的平台,以及要发挥其潜力还需要解决哪些问题。

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