Department of Chemistry, University of Massachusetts, Amherst, 01003, USA.
Adv Drug Deliv Rev. 2013 Jan;65(1):93-9. doi: 10.1016/j.addr.2012.08.011. Epub 2012 Sep 4.
Inorganic nanomaterials have an array of structural and physical properties that can be used in therapeutic delivery systems. The sizes, shapes, and surfaces of inorganic nanomaterials can be tailored to produce distinct interactions with biological systems both in vitro and in vivo. Nanoparticle cores can likewise be engineered to possess unique opticophysical properties, including upconversion, size-dependent absorbance/emission as well as magnetic properties such as superparamagnetism. These properties make inorganic nanomaterials as useful imaging agents for noninvasive diagnostics and remotely activated theragnostics. Taken together, these unique properties of inorganic nanomaterials make them promising delivery systems.
无机纳米材料具有一系列的结构和物理特性，可用于治疗性递药系统。无机纳米材料的尺寸、形状和表面可以进行定制，以产生与体外和体内生物系统的独特相互作用。纳米颗粒核心同样可以被设计为具有独特的光学物理特性，包括上转换、尺寸依赖性的吸收/发射以及超顺磁性等磁性特性。这些特性使得无机纳米材料成为用于非侵入性诊断和远程激活治疗的有用成像剂。综上所述，无机纳米材料的这些独特特性使它们成为有前途的递药系统。
