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经保守治疗的聚乙二醇电解质溶液所致吸入性肺炎

Aspiration pneumonitis caused by polyethylene glycol-electrolyte solution treated with conservative management.

作者信息

Mosquera Ricardo A, McDonald Mark, Samuels Cheryl

机构信息

High Risk Children Comprehensive Care Clinic, University of Texas Health Science of Houston, 6410 Fannin Street, Suite 500, Houston, TX 77030, USA.

出版信息

Case Rep Pediatr. 2014;2014:872634. doi: 10.1155/2014/872634. Epub 2014 May 18.

DOI:10.1155/2014/872634
PMID:24955273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4052121/
Abstract

Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his right lung following migration of his nasogastric tube (NGT). Hypoxemia and tachypnea without respiratory failure were observed after infusion. Because PEG is a nonabsorbable toxic material, previous case reports have advocated for the performance of bronchoalveolar lavage (BAL) in the treatment of PEG pneumonitis. With close monitoring, our patient was able to be successfully treated without the need for invasive interventions including BAL or intubation. Generalizations about PEG absorption in the lung based on its permeability in the gastrointestinal tract should not deter the use of more conservative treatment in the appropriate patient.

摘要

聚乙二醇(PEG)电解质溶液,即复方聚乙二醇电解质散,是一种常用于术前肠道清洁的渗透性泻药。在本病例报告中,一名9岁男孩在鼻胃管(NGT)移位后,PEG溶液意外注入右肺,随后发生了吸入性肺炎。输注后观察到低氧血症和呼吸急促,但无呼吸衰竭。由于PEG是一种不可吸收的有毒物质,既往病例报告主张采用支气管肺泡灌洗(BAL)治疗PEG肺炎。通过密切监测,我们的患者得以成功治疗,无需包括BAL或插管在内的侵入性干预措施。基于PEG在胃肠道的渗透性而对其在肺部吸收情况进行的归纳,不应妨碍对合适患者采用更保守的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a51/4052121/3ebd72b50921/CRIPE2014-872634.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a51/4052121/3ebd72b50921/CRIPE2014-872634.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a51/4052121/3ebd72b50921/CRIPE2014-872634.001.jpg

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