Sethi S K, Ghafoor M A, Vandepitte J
Department of Microbiology, Faculty of Medicine, Kuwait University, Safat.
Eur J Pediatr. 1989 Jan;148(4):368-70. doi: 10.1007/BF00444136.
Six newborns with Listeria monocytogenes infection were admitted to the same neonatal unit between 31 October and 3 December 1985. The index case, a preterm baby, was born to a mother who was febrile with an influenza-like illness at the time of delivery. This baby presented with Listeria sepsis and pneumonia. Another child was born from whose mother L. monocytogenes was isolated from the cervix with the same serotype as that in the CSF of her newborn. In the other cases blood and cervical cultures of the mothers were negative, while Listeria was isolated from the CSF of their babies. Five out of six infants developed meningitis between 9 and 12 days after birth. All isolates were serotype 4b and indistinguishable by phage typing. All babies were successfully treated without any major sequelae. Although cross-infection was strongly suggested, the source of the outbreak could not be established. This is the first documented report of human listeriosis in Kuwait.
1985年10月31日至12月3日期间，六名感染单核细胞增生李斯特菌的新生儿被收治于同一新生儿病房。首例病例是一名早产儿，其母亲在分娩时发热，患有流感样疾病。该婴儿出现了李斯特菌败血症和肺炎。另一名婴儿的母亲宫颈分离出单核细胞增生李斯特菌，其血清型与新生儿脑脊液中的相同。在其他病例中，母亲的血液和宫颈培养均为阴性，但在其婴儿的脑脊液中分离出了李斯特菌。六名婴儿中有五名在出生后9至12天内患上脑膜炎。所有分离株均为4b血清型，通过噬菌体分型无法区分。所有婴儿均成功治愈，无任何严重后遗症。尽管强烈提示存在交叉感染，但此次暴发的源头无法确定。这是科威特首例有记录的人类李斯特菌病报告。
