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使用MatriStem细胞外基质异种移植物加速复杂开放性藏毛窦伤口的愈合:9例病例

Accelerated healing of complex open pilonidal wounds using MatriStem extracellular matrix xenograft: nine cases.

作者信息

Sasse Kent C, Brandt Jared, Lim Dionne C, Ackerman Ellen

机构信息

Clinical Faculty, University of Nevada, Reno, NV, USA

Sasse Surgical Associates, Reno, NV, USA.

出版信息

J Surg Case Rep. 2013 Apr 15;2013(4):rjt025. doi: 10.1093/jscr/rjt025.

Abstract

Complex open pilonidal wounds represent a challenging wound healing problem. Nine cases of complex open pilonidal wounds are described. Each of them was treated at the time of primary wide excision with placement of xenograft extracellular matrix material derived from urinary bladder (MatriStem, ACell Corporation). The patients left the xenograft material and dressings intact and returned to our clinic at weekly intervals for inspection of the wounds. All of the cases of complex open pilonidal wounds healed without infection and without requiring re-operation. The average time to healing in this series was 7 weeks. Treatment of complex open pilonidal wounds with MatriStem extracellular matrix derived from urinary bladder in this fashion results in favorable wound healing of complex open pilonidal wounds.

摘要

复杂开放性藏毛窦伤口是一个具有挑战性的伤口愈合问题。本文描述了9例复杂开放性藏毛窦伤口。每例患者均在初次广泛切除时接受治疗,同时植入源自膀胱的异种移植细胞外基质材料(MatriStem,ACell公司)。患者让异种移植材料和敷料保持完整,每周返回我们的诊所检查伤口。所有复杂开放性藏毛窦伤口病例均愈合良好,无感染且无需再次手术。本系列病例的平均愈合时间为7周。以这种方式使用源自膀胱的MatriStem细胞外基质治疗复杂开放性藏毛窦伤口,可使复杂开放性藏毛窦伤口实现良好的愈合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e37b/3635226/ddd1e133f832/rjt02501.jpg

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