Zlotnik Yair, Plakht Ygal, Aven Anna, Engel Yael, Am Neta Bar, Ifergane Gal
Department of Neurology, Headache Clinic, Beer-Sheva, Israel.
Department of Neurology, Headache Clinic, Beer-Sheva, Israel ; Unit of Nursing Research, Soroka University Medical Center, Beer-Sheva, Israel.
J Neurosci Rural Pract. 2014 Apr;5(2):128-34. doi: 10.4103/0976-3147.131652.
Alcohol hangover is a poorly understood cluster of symptoms occurring following a heavy consumption of alcohol. The term "delayed alcohol-induced headache" is often used synonymously. Our objective was to compare alcohol hangover symptoms in migraine sufferers and nonsufferers.
In this cross-sectional study, university students were asked to fill structured questionnaires assessing headache history, alcoholic consumption, and hangover symptoms (using the Hangover Symptom Scale (HSS)). Subjects were classified as suffering from migraine with or without aura and nonsufferers according the International Classification of Headache Disorders 2(nd) Edition (ICHD-II). The 13 hangover symptoms were divided by the researches into migraine-like and other nonmigraine-like symptoms.
Hangover symptoms among 95 migraine sufferers and 597 nonsufferers were compared. Migraine sufferers consumed less alcohol compared with the nonsufferers (mean drinks/week 2.34 ± 4.11 vs. 2.92 ± 3.58, P = 0.038) and suffered from higher tendency to migraine-like symptoms after drinking (mean 2.91 ± 3.43 vs. 1.85 ± 2.35, P = 0.002) but not to other hangover symptoms (mean 5.39 ± 6.31 vs. 4.34 ± 4.56, P = 0.1).
Migraine sufferers consume less alcohol, especially beer and liquors, and are more vulnerable to migraine-like hangover symptoms than nonsufferers. The finding that the tendency to develop migraine attacks affects the hangover symptomatology may suggest a similarity in pathophysiology, and possibly in treatment options.
酒精宿醉是大量饮酒后出现的一组难以理解的症状。术语“延迟性酒精性头痛”常被用作同义词。我们的目的是比较偏头痛患者和非偏头痛患者的酒精宿醉症状。
在这项横断面研究中，大学生被要求填写结构化问卷，评估头痛病史、饮酒情况和宿醉症状（使用宿醉症状量表（HSS））。根据《国际头痛疾病分类第2版》（ICHD-II），受试者被分为有或无先兆偏头痛患者和非偏头痛患者。研究人员将13种宿醉症状分为偏头痛样症状和其他非偏头痛样症状。
比较了95名偏头痛患者和597名非偏头痛患者的宿醉症状。与非偏头痛患者相比，偏头痛患者饮酒量较少（平均每周饮酒量2.34±4.11 vs. 2.92±3.58，P = 0.038），饮酒后出现偏头痛样症状的倾向更高（平均2.91±3.43 vs. 1.85±2.35，P = 0.002），但其他宿醉症状无差异（平均5.39±6.31 vs. 4.34±4.56，P = 0.1）。
偏头痛患者饮酒量较少，尤其是啤酒和烈性酒，并且比非偏头痛患者更容易出现偏头痛样宿醉症状。偏头痛发作倾向影响宿醉症状的这一发现可能表明其病理生理学存在相似性，治疗选择可能也相似。
