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一名屠宰场工人感染致死性猪链球菌败血症

Fatal Streptococcus suis septicemia in an abattoir worker.

作者信息

Büngener W, Bialek R

机构信息

Hafenkrankenhaus, Hamburg, FRG.

出版信息

Eur J Clin Microbiol Infect Dis. 1989 Apr;8(4):306-8. doi: 10.1007/BF01963457.

DOI:10.1007/BF01963457
PMID:2497004
Abstract

A 51-year-old abattoir worker became ill with high fever and was admitted to hospital late in the evening, where he died 4 h later. Smears of peripheral blood taken 7 h after death showed numerous cocci. Cultures of the blood grew beta-hemolytic streptococci exhibiting the biochemical properties of Streptococcus suis II. A complete autopsy with extensive microscopical studies showed numerous bacteria in small vessels of several organs, but no bacterial colonisation of tissues, meningitis, or other relevant lesions were found. The group R antigen of the bacteria could be demonstrated by immunofluorescence in paraffin sections of the kidney and the adrenal gland. Two similar cases of fulminant fatal Streptococcus suis II septicemia have been reported from Denmark. This appears to be the first case observed in the Federal Republic of Germany.

摘要

一名51岁的屠宰场工人因高烧生病,傍晚时被送往医院,4小时后死亡。死后7小时采集的外周血涂片显示有大量球菌。血液培养物中生长出具有猪链球菌II生化特性的β-溶血性链球菌。全面的尸检及广泛的显微镜检查显示,多个器官的小血管中有大量细菌,但未发现组织细菌定植、脑膜炎或其他相关病变。通过免疫荧光法可在肾脏和肾上腺的石蜡切片中检测到该细菌的R群抗原。丹麦已报告了两例类似的猪链球菌II暴发性致死败血症病例。这似乎是德意志联邦共和国观察到的首例病例。

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本文引用的文献

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Group R streptococci pathogenic for man. Two cases of meningitis and one fatal case of sepsis.对人类致病的R组链球菌。两例脑膜炎病例和一例败血症死亡病例。
Acta Pathol Microbiol Scand. 1968;74(1):69-76.
2
Meningitis caused by Streptococcus suis: case report and review of the literature.猪链球菌引起的脑膜炎:病例报告及文献综述
Infection. 1986 Jul-Aug;14(4):181-5. doi: 10.1007/BF01645260.
3
[Serious infections in man caused by group R streptococci].R 族链球菌引起的人类严重感染
猪链球菌的溶菌酶抗性具有高度可变性和多因素性。
PLoS One. 2012;7(4):e36281. doi: 10.1371/journal.pone.0036281. Epub 2012 Apr 30.
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Streptococcus suis meningitis: First case reported in Quebec.猪链球菌脑膜炎:魁北克省首例报告病例。
Can J Infect Dis. 1996 Sep;7(5):329-31. doi: 10.1155/1996/354693.
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Lgt processing is an essential step in Streptococcus suis lipoprotein mediated innate immune activation.Lgt 加工是猪链球菌脂蛋白介导固有免疫激活的一个重要步骤。
PLoS One. 2011;6(7):e22299. doi: 10.1371/journal.pone.0022299. Epub 2011 Jul 19.
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J Bacteriol. 2011 Oct;193(19):5073-80. doi: 10.1128/JB.05305-11. Epub 2011 Jul 22.
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Autopsy report of four cases who died from Streptococcus suis infection, with a review of the literature.4例死于猪链球菌感染病例的尸检报告及文献复习
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