Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Vet Microbiol. 2014 Aug 27;172(3-4):505-10. doi: 10.1016/j.vetmic.2014.05.033. Epub 2014 Jun 7.
Based upon prior studies, domestic cats have been shown to be the natural reservoir for Bartonella henselae, Bartonella clarridgeiae and Bartonella koehlerae. However, other Bartonella species, such as Bartonella vinsonii subsp. berkhoffii, Bartonella quintana or Bartonella bovis (ex weissii) have been either isolated from or Bartonella DNA sequences PCR amplified and sequenced. In the late 1980s, before B. henselae was confirmed as the etiological agent of cat scratch disease, Afipia felis had been proposed as the causative agent. In order to determine the feline susceptibility to A. felis, B. vinsonii subsp. berkhoffii, Bartonella rochalimae, B. quintana or B. bovis, we sought to detect the presence of bacteremia and seroconversion in experimentally-inoculated cats. Most of the cats seroconverted, but only the cats inoculated with B. rochalimae became bacteremic, indicating that cats are not natural hosts of A. felis or the other Bartonella species or subspecies tested in this study.
基于先前的研究，已表明家猫是巴尔通体菌属亨氏亚种、巴尔通体菌属克拉里吉氏亚种和巴尔通体菌属科勒雷氏亚种的天然宿主。然而，其他巴尔通体菌属物种，如巴尔通体菌属伍氏亚种、巴尔通体菌属 quintana 或巴尔通体菌属 bovis（前 weissii），已经从猫中分离出来，或通过 PCR 扩增和测序检测到其 DNA 序列。在 20 世纪 80 年代后期，在巴尔通体菌属亨氏亚种被确认为猫抓病的病原体之前，阿菲波菌属 felis 曾被提议为病原体。为了确定猫对阿菲波菌属 felis、巴尔通体菌属伍氏亚种、巴尔通体菌属 rochalimae、巴尔通体菌属 quintana 或巴尔通体菌属 bovis 的易感性，我们试图检测实验接种猫的菌血症和血清转化。大多数猫发生了血清转化，但只有接种巴尔通体菌属 rochalimae 的猫发生了菌血症，这表明猫不是阿菲波菌属 felis 或本研究中测试的其他巴尔通体菌属物种或亚种的天然宿主。
