Canny G J, Szeinberg A, Koreska J, Levison H
Division of Chest Diseases, Hospital for Sick Children, Toronto, Canada.
Pediatr Pulmonol. 1989;6(3):169-71. doi: 10.1002/ppul.1950060308.
Arterialized blood gases were analyzed in 143 patients with Duchenne muscular dystrophy (DMD) to assess the relationship between forced vital capacity (FVC) and hypercapnia. The majority of patients studied had PaCO2 values in the low or normal range. Only six older patients had hypercapnia (PaCO2 greater than or equal to 45 mm Hg), and all these patients had FVC values less than or equal to 40% predicted. We conclude that hypercapnic respiratory failure occurs as a late preterminal event in DMD.
对143例杜氏肌营养不良症（DMD）患者的动脉化血气进行分析，以评估用力肺活量（FVC）与高碳酸血症之间的关系。大多数研究患者的动脉血二氧化碳分压（PaCO2）值处于低或正常范围。只有6例年龄较大的患者出现高碳酸血症（PaCO2大于或等于45 mmHg），且所有这些患者的FVC值均小于或等于预测值的40%。我们得出结论，高碳酸血症性呼吸衰竭是DMD晚期临终前的事件。
