Xia Ji-Bao, Ma Yuyong, Chen Chuo
Org Chem Front. 2014 Jul 1;1(5):468-472. doi: 10.1039/C4QO00057A.
Vanadium(III) oxide catalyzes the direct fluorination of C(sp)-H groups with Selectfluor. This reaction is operationally simple. The catalyst and the reaction byproduct can be removed easily by filtration. Using this method, a fluorine atom can be introduced to the tertiary position of 1,4-cineole and L-menthone selectively.
三氧化二钒催化用Selectfluor对C(sp)-H基团进行直接氟化反应。该反应操作简单。催化剂和反应副产物可通过过滤轻松除去。使用此方法，可以将氟原子选择性地引入1,4-桉叶素和L-薄荷酮的叔位。
