School of Nursing & Midwifery, University of South Australia, Room 44, Level 6, Centenary Building, North Terrace, Adelaide, South Australia 5000, Australia.
Flinders Centre for Innovation in Cancer Flinders University, Bedford Park, South Australia 5042, Australia.
Br J Cancer. 2014 Aug 26;111(5):970-5. doi: 10.1038/bjc.2014.371. Epub 2014 Jul 1.
Occult blood-based colorectal cancer (CRC) screening may result in adverse psychological outcomes for participants. The aims of this study were to measure the psychological consequences of participating in screening at key points along the screening and diagnostic pathway, and examine variation over time within or between test outcome groups.
A total of 301 people (positives=165, negatives=136) aged 50-76 years were surveyed via validated psychological questionnaires after result notification, post colonoscopy (positives only) and 1 year following result notification.
Negatives scored significantly higher in quality of life domains and lower state anxiety, anger and depression in comparison to positives both after result notification and at 1 year follow-up. Positives had significantly decreased state anxiety and depression at 1 year and improvement in HLoC power and reduced screening decision doubtfulness post colonoscopy. Positives experienced heightened CRC risk perception both after result notification and at 1 year follow-up in comparison to negatives, but reported less difficulty participating in ongoing screening.
In positives, increased anxiety and doubtfulness about the decision to screen declined over time. Lower CRC risk perception in negatives indicates the need for education to promote CRC screening participation.
潜血的结直肠癌（CRC）筛查可能会给参与者带来不良的心理后果。本研究的目的是在筛查和诊断途径的关键点上测量参与筛查的心理后果，并在测试结果组内或组间随时间变化进行检验。
共有 301 名 50-76 岁的参与者（阳性=165，阴性=136）在结果通知后、结肠镜检查后（仅阳性）和结果通知后 1 年通过验证的心理问卷进行调查。
与阳性组相比，阴性组在生活质量各领域的评分明显更高，状态焦虑、愤怒和抑郁的评分明显更低，无论是在结果通知后还是在 1 年随访时都是如此。阳性组在 1 年后的状态焦虑和抑郁明显下降，结肠镜检查后 HLoC 功率提高，筛查决策不确定性减少。与阴性组相比，阳性组在结果通知后和 1 年随访时的 CRC 风险感知明显增加，但报告的参与持续筛查的困难较少。
在阳性组中，对筛查决策的焦虑和疑虑随时间的推移而下降。阴性组 CRC 风险感知较低表明需要进行教育，以促进 CRC 筛查的参与。
