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“原发性”抗磷脂综合征中的复发性深静脉血栓形成和艾迪生病

Recurrent deep vein thrombosis and Addison's disease in "primary" antiphospholipid syndrome.

作者信息

Asherson R A, Hughes G R

机构信息

Lupus Arthritis Research Unit, Rayne Institute, St. Thomas' Hospital, London, England.

出版信息

J Rheumatol. 1989 Mar;16(3):378-80.

PMID:2498514
Abstract

We describe a 43-year-old Caucasian man who, after a 10 year history of recurrent deep vein thromboses and pulmonary emboli, was found to have a "lupus anticoagulant" and marked elevation of antibodies to cardiolipin. He subsequently developed skin and buccal pigmentation and biochemical investigations revealed the presence of Addison's disease. The relationship of the Addison's disease to the recurrent thrombotic events in the presence of antibodies to phospholipids is discussed.

摘要

我们描述了一名43岁的白种男性，在有10年复发性深静脉血栓形成和肺栓塞病史后，发现其存在“狼疮抗凝物”且抗心磷脂抗体显著升高。随后他出现了皮肤和颊部色素沉着，生化检查显示存在艾迪生病。本文讨论了在存在磷脂抗体的情况下，艾迪生病与复发性血栓事件之间的关系。

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Recurrent deep vein thrombosis and Addison's disease in "primary" antiphospholipid syndrome.“原发性”抗磷脂综合征中的复发性深静脉血栓形成和艾迪生病
J Rheumatol. 1989 Mar;16(3):378-80.
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Occlusion of small hepatic veins associated with systemic lupus erythematosus with the lupus anticoagulant and anti-cardiolipin antibody.与系统性红斑狼疮相关的小肝静脉闭塞，伴有狼疮抗凝物和抗心磷脂抗体。
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[Relation of antiphospholipid antibodies to thrombotic phenomena and clinical activity of systemic lupus erythematosus].[抗磷脂抗体与血栓形成现象及系统性红斑狼疮临床活动的关系]
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N Engl J Med. 1990 Mar 15;322(11):754-69. doi: 10.1056/NEJM199003153221108.

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