Rapid repression of quiescence-specific gene expression by epidermal growth factor, insulin, and pp60v-src.
作者信息
Bedard P A, Yannoni Y, Simmons D L, Erikson R L
机构信息
Department of Cellular and Developmental Biology, Harvard University, Cambridge, Massachusetts 02138.
出版信息
Mol Cell Biol. 1989 Mar;9(3):1371-5. doi: 10.1128/mcb.9.3.1371-1375.1989.
Abstract
We isolated a cDNA for p20K, a secreted protein preferentially synthesized in nonproliferating cells. p20K mRNA and protein levels declined rapidly following treatment with various mitogens. DNA sequence analysis of the p20K cDNA predicted a novel protein distantly related to alpha 2 mu-globulin and plasma retinol-binding protein.
摘要
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