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伴有水疱的严重急性泛发性脓疱病,类似中毒性表皮坏死松解症,与原发性腮腺炎感染相关。

Severe acute generalized exanthematous pustulosis with blistering mimicking toxic epidermal necrolysis, associated with a primary mumps infection.

作者信息

Azib S, Florin V, Fourrier F, Delaporte E, Staumont-Sallé D

机构信息

CHRU, Lille, France.

出版信息

Clin Exp Dermatol. 2014 Aug;39(6):723-5. doi: 10.1111/ced.12384. Epub 2014 Jul 1.

DOI:10.1111/ced.12384
PMID:24986490
Abstract

Acute generalized exanthematous pustulosis (AGEP) is a severe adverse cutaneous reaction, which is mostly due to drugs, but which has also been described as occurring after infections. We report a case of severe AGEP with extensive blistering mimicking toxic epidermal necrolysis (TEN) in a 47-year-old woman. This was associated with a life-threatening primary mumps infection, complicated by perimyocarditis and encephalitis. The recent increase in the incidence of mumps should lead physicians to be aware of the uncommon clinical features and complications of this disease.

摘要

急性泛发性脓疱性皮病(AGEP)是一种严重的皮肤不良反应,主要由药物引起,但也有报道称感染后会发生。我们报告一例47岁女性发生的严重AGEP,伴有广泛水疱,类似中毒性表皮坏死松解症(TEN)。这与危及生命的原发性腮腺炎感染有关,并伴有心包心肌炎和脑炎。近期腮腺炎发病率的上升应使医生意识到该疾病不常见的临床特征和并发症。

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