Pourhossein Zohreh, Qotbi Ali Ahmad Alaw, Seidavi Alireza, Laudadio Vito, Centoducati Gerardo, Tufarelli Vincenzo
Department of Animal Science, Rasht Branch, Islamic Azad University, Rasht, Iran.
Anim Sci J. 2015 Jan;86(1):105-10. doi: 10.1111/asj.12250. Epub 2014 Jul 2.
This experiment was conducted to evaluate the effects of different levels of sweet orange (Citrus sinensis) peel extract (SOPE) on humoral immune system responses in broiler chickens. Three hundred 1-day broilers (Ross-308) were randomly allocated to treatments varying in supplemental SOPE added in the drinking water. The experimental groups consisted of three treatments fed for 42 days as follows: a control treatment without feed extract, a treatment containing 1000 ppm of SOPE and a treatment containing 1250 ppm of SOPE. All treatments were isocaloric and isonitrogenous. Broilers were vaccinated with Newcastle disease virus (NDV), avian influenza (AI), infectious bursal disease (IBD) and infectious bronchitis virus (IBV) vaccines. Antibody titer response to sheep red blood cells (SRBC) was higher in the group fed 1250 ppm of SOPE (P < 0.05) as well as for immunoglobulin G (IgG) and IgM. Similarly, antibody titer responses to all vaccines were constantly elevated (P < 0.05) by SOPE enrichment in a dose-dependent manner. Relative weights of spleen and bursa of Fabricius were unaffected by treatments. Dietary SOPE supplementation may improve the immune response and diseases resistance, indicating that it can constitute a useful additive in broiler feeding. Thus, supplying SOPE in rations may help to improve relative immune response in broiler chickens.
本实验旨在评估不同水平的甜橙（Citrus sinensis）果皮提取物（SOPE）对肉鸡体液免疫系统反应的影响。300只1日龄肉鸡（罗斯308）被随机分配到饮用水中添加不同水平SOPE的处理组。实验组包括三个处理组，喂养42天，具体如下：一个不添加饲料提取物的对照组，一个含有1000 ppm SOPE的处理组和一个含有1250 ppm SOPE的处理组。所有处理组的热量和氮含量均相同。肉鸡接种了新城疫病毒（NDV）、禽流感（AI）、传染性法氏囊病（IBD）和传染性支气管炎病毒（IBV）疫苗。饲喂1250 ppm SOPE的组对绵羊红细胞（SRBC）的抗体滴度反应更高（P < 0.05），免疫球蛋白G（IgG）和IgM也是如此。同样，SOPE以剂量依赖的方式持续提高了对所有疫苗的抗体滴度反应（P < 0.05）。脾脏和法氏囊的相对重量不受处理的影响。日粮中添加SOPE可能会改善免疫反应和抗病能力，表明它可以成为肉鸡饲养中的一种有用添加剂。因此，在日粮中添加SOPE可能有助于提高肉鸡的相对免疫反应。
