Whelan Noella W, Steenbeek Audrey, Martin-Misener Ruth, Scott Jeffrey, Smith Bruce, D'Angelo-Scott Holly
School of Nursing, Dalhousie University, Canada.
School of Nursing, Dalhousie University, Canada; Canadian Center for Vaccinology, IWK Health Centre, Canada.
Vaccine. 2014 Aug 6;32(36):4665-71. doi: 10.1016/j.vaccine.2014.06.026. Epub 2014 Jun 30.
Nova Scotia has the highest rate of cervical cancer in Canada, and most of these cases are attributed to the Human Papillomavirus (HPV). In 2007, Gardasil(®) was approved and implemented in a successful school-based HPV immunization program. Little is known, however, which strategies (if any) used within a school-based program help to improve vaccine uptake.
A retrospective, exploratory correlation study was conducted to examine the relationship between school-based strategies and uptake of HPV vaccine. Data was analyzed through Logistic regression, using PASW Statistics 17 (formerly SPSS 17).
HPV vaccine initiation was significantly associated with Public Health Nurses providing reminder calls for: consent return (p=0.017) and missed school clinic (p=0.004); HPV education to teachers (p<0.001), and a thank-you note to teachers (p<0.001). Completion of the HPV series was associated with vaccine consents being returned to the students' teacher (p=0.003), and a Public Health Nurse being assigned to a school (p=0.025).
These findings can be used to help guide school-based immunization programs for optimal uptake of the HPV vaccine among the student population.
新斯科舍省的宫颈癌发病率在加拿大最高,且大多数病例归因于人乳头瘤病毒(HPV)。2007年,加德西(®)疫苗获批并在一项成功的以学校为基础的HPV免疫计划中实施。然而,对于在以学校为基础的计划中采用的哪些策略(如果有的话)有助于提高疫苗接种率,人们知之甚少。
开展了一项回顾性探索性相关性研究,以检验以学校为基础的策略与HPV疫苗接种之间的关系。使用PASW Statistics 17(原SPSS 17)通过逻辑回归分析数据。
HPV疫苗起始接种与公共卫生护士进行以下提醒电话显著相关:同意书返还提醒(p = 0.017)和错过学校诊所接种提醒(p = 0.004);对教师进行HPV教育(p < 0.001),以及给教师的感谢信(p < 0.001)。HPV系列疫苗接种完成与将疫苗同意书返还给学生的教师(p = 0.003)以及为学校分配一名公共卫生护士(p = 0.025)相关。
这些发现可用于指导以学校为基础的免疫计划,以实现学生群体中HPV疫苗的最佳接种率。