Li Xiaoke, Wang Jinfang, Joiner Andrew, Chang Jiang
Unilever Oral Care, 66 Linxin Road, Shanghai, 200335, China.
Unilever Oral Care, 66 Linxin Road, Shanghai, 200335, China.
J Dent. 2014 Jun;42 Suppl 1:S12-20. doi: 10.1016/S0300-5712(14)50003-6.
The purpose of this paper is to review current knowledge and technologies for tooth remineralisation.
The literature was searched using the "Scopus" and "Web of Knowledge" database from the year 1971, with principal key words of miner, teeth and enamel. Language was restricted to English. Original studies and reviews were included. Conference papers and posters were excluded.
The importance of oral health for patients and consumers has seen a steady increase in the number of tooth remineralisation agents, products and procedures over recent years. Concomitantly, there has been continued publication of both in vivo and in vitro tooth remineralisation and demineralisation studies. It is clear that fluoride treatments are generally effective in helping to protect the dental enamel from demineralisation and enhancing remineralisation. Continued efforts to increase the efficacy of fluoride have been made, in particular, by the addition of calcium salts or calcium containing materials to oral care products which may enhance the delivery and retention of fluoride into the oral cavity. In addition, the calcium salts or materials may act as additional sources of calcium to promote enamel remineralisation or reduce demineralisation processes. Inspired by the concept of bioactive materials for bone repair and regeneration, bioglass and in particular calcium silicate type materials show potential for enamel health benefits and is a growing area of research.
本文旨在综述当前牙齿再矿化的相关知识和技术。
使用“Scopus”和“Web of Knowledge”数据库检索1971年以来的文献,主要关键词为“矿物质”、“牙齿”和“牙釉质”。语言限定为英语。纳入原始研究和综述。排除会议论文和海报。
近年来,口腔健康对患者和消费者的重要性日益凸显,牙齿再矿化剂、产品和程序的数量不断增加。与此同时,体内和体外牙齿再矿化及脱矿化研究持续发表。显然,氟化物治疗通常在帮助保护牙釉质免受脱矿化和增强再矿化方面有效。特别是通过在口腔护理产品中添加钙盐或含钙材料来提高氟化物的功效,这可能会增强氟化物在口腔中的递送和保留。此外,钙盐或材料可作为额外的钙源,促进牙釉质再矿化或减少脱矿化过程。受用于骨修复和再生的生物活性材料概念的启发,生物玻璃尤其是硅酸钙类材料对牙釉质健康有益,是一个不断发展的研究领域。