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影响耳鸣严重程度的社会人口统计学、健康状况及与耳鸣相关的变量。

Socio-demographic, health, and tinnitus related variables affecting tinnitus severity.

作者信息

Hoekstra Carlijn E L, Wesdorp Francina M, van Zanten Gijsbert A

机构信息

1Department of Otorhinolaryngology and Head & Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands; 2Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands; and 3Faculty of Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Ear Hear. 2014 Sep-Oct;35(5):544-54. doi: 10.1097/AUD.0000000000000045.

DOI:10.1097/AUD.0000000000000045
PMID:25003528
Abstract

OBJECTIVES

Tinnitus is a highly prevalent symptom with potential severe morbidity. Fortunately, only a small proportion of the population experience problems due to their tinnitus in such a degree that it adversely affects their quality of life (clinically significant tinnitus). It is not known why these individuals develop more burden from tinnitus. It seems likely that the severity of tinnitus can be influenced by different factors, such as socio-demographic or tinnitus characteristics or additional health complaints. It remains unclear from the current literature as to what are the main independent variables that have a bearing on tinnitus severity. This study addresses this problem by investigating variables previously described in the literature as well as additional variables. The aim of this study is to identify socio-demographic, health, and tinnitus variables that independently relate to tinnitus severity the most.

DESIGN

This is a retrospective cohort study performed at the Tinnitus Care Group of the University Medical Center, Utrecht, in 309 consecutively seen chronic tinnitus patients. At this care group, patients are examined according to a structured diagnostic protocol, including history-taking by an otorhinolaryngologist and audiologist, physical examination, and audiometry. Based on results from previous research and theoretical considerations, a subset of data acquired through this diagnostic protocol were selected and used in this study. Univariate and multivariate correlations with tinnitus severity were investigated for 28 socio-demographic, health, and tinnitus variables. Tinnitus severity was measured with the Tinnitus Questionnaire (TQ) and the Tinnitus Handicap Inventory (THI).

RESULTS

Eighteen variables related univariately with the TQ and 16 variables related univariately with the THI. Among these, 14 variables related univariately with both the TQ and the THI. Multivariate analyses showed three variables with an independent significant effect on both the TQ and the THI: percentage of tinnitus awareness during the day, self-reported depression and/or anxiety, and loudness on a Visual Analogue Scale. Three additional variables contributed independently significantly to the explained variance in either the TQ or the THI: level of education, somatic complaints, and tinnitus variability in loudness and/or pitch on a Visual Analogue Scale. These variables were among the first not to reach significance on the other questionnaire.

CONCLUSIONS

Tinnitus severity is shown to be strongly related to percentage of tinnitus awareness during the day, self-reported depression and/or anxiety, subjectively experienced loudness, level of education, existence of additional somatic complaints, and subjectively experienced variability in loudness and/or pitch. Further research is needed to investigate the causal relationship between these variables and tinnitus severity. This knowledge may contribute to a better recognition, follow-up, and/or counseling of more vulnerable patients.

摘要

目的

耳鸣是一种非常普遍的症状,可能导致严重的发病率。幸运的是,只有一小部分人因耳鸣而出现严重影响其生活质量的问题(临床上有意义的耳鸣)。目前尚不清楚为什么这些人会因耳鸣而承受更多负担。耳鸣的严重程度似乎可能受到不同因素的影响,如社会人口统计学因素、耳鸣特征或其他健康问题。从目前的文献中尚不清楚哪些是影响耳鸣严重程度的主要独立变量。本研究通过调查文献中先前描述的变量以及其他变量来解决这个问题。本研究的目的是确定与耳鸣严重程度最独立相关的社会人口统计学、健康和耳鸣变量。

设计

这是一项在乌得勒支大学医学中心耳鸣护理组进行的回顾性队列研究,共纳入309例连续就诊的慢性耳鸣患者。在这个护理组中,患者按照结构化诊断方案进行检查,包括耳鼻喉科医生和听力学家的病史采集、体格检查和听力测定。基于先前研究的结果和理论考虑,从该诊断方案获取的数据子集中选择并用于本研究。对28个社会人口统计学、健康和耳鸣变量与耳鸣严重程度进行单变量和多变量相关性研究。耳鸣严重程度用耳鸣问卷(TQ)和耳鸣障碍量表(THI)进行测量。

结果

18个变量与TQ单变量相关,16个变量与THI单变量相关。其中,14个变量与TQ和THI均单变量相关。多变量分析显示,有3个变量对TQ和THI均有独立的显著影响:白天耳鸣知晓率、自我报告的抑郁和/或焦虑以及视觉模拟量表上的响度。另外3个变量对TQ或THI的解释方差有独立的显著贡献:教育水平、躯体症状以及视觉模拟量表上耳鸣响度和/或音高的变异性。这些变量是在另一份问卷上首次未达到显著性的变量之一。

结论

耳鸣严重程度与白天耳鸣知晓率、自我报告的抑郁和/或焦虑、主观感受的响度、教育水平、是否存在其他躯体症状以及主观感受的响度和/或音高变异性密切相关。需要进一步研究来调查这些变量与耳鸣严重程度之间的因果关系。这些知识可能有助于更好地识别、随访和/或咨询更易受影响的患者。

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