Tachibana N, Sugita Y, Teshima Y, Hishikawa Y
Department of Neuropsychiatry, Osaka University Medical School, Japan.
Jpn J Psychiatry Neurol. 1989 Mar;43(1):77-84. doi: 10.1111/j.1440-1819.1989.tb02554.x.
We reported the case of a 13-year-old anorectic girl with epileptic seizures who showed marked favorable responses to sodium valproate and clonazepam. These two anticonvulsants were effective not only for controlling her epileptic seizures, but also against anorexia nervosa itself. The mechanism of their action to anorexia nervosa is unknown, but repeated EEGs and a trial of sodium valproate with or without clonazepam may be useful in evaluating the diverse pathologies of anorexia nervosa which seems to be a heterogeneous clinical entity.
我们报告了一例13岁患有癫痫发作的神经性厌食女孩的病例,该女孩对丙戊酸钠和氯硝西泮表现出显著的良好反应。这两种抗惊厥药不仅对控制她的癫痫发作有效,而且对神经性厌食症本身也有效。它们对神经性厌食症的作用机制尚不清楚,但重复进行脑电图检查以及使用或不使用氯硝西泮的丙戊酸钠试验可能有助于评估神经性厌食症的多种病理情况,因为神经性厌食症似乎是一种异质性的临床实体。