Xiao Tiebo, Zhang Ping, Xie Yang, Wang Jun, Zhou Lei
School of Chemistry and Chemical Engineering, Sun Yat-Sen University, 135 Xingang West Road, Guangzhou 510275, China.
Org Biomol Chem. 2014 Aug 28;12(32):6215-22. doi: 10.1039/c4ob00614c.
A general source of dialkoxycarbenes, 2,2-dialkoxy-5,5-dimethyl-Δ(3)-1,3,4-oxadiazolines, have been successfully employed as coupling partners in CuI-catalyzed cross-coupling reactions with terminal alkynes, which afforded various unsymmetrical propargylic acetals in good yields.
二烷氧基卡宾的一种常见来源，即2,2 - 二烷氧基 - 5,5 - 二甲基 - Δ(3)-1,3,4 - 恶二唑啉，已成功用作与末端炔烃进行CuI催化交叉偶联反应的偶联伙伴，该反应以良好的产率得到了各种不对称炔丙基缩醛。
