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美国退伍军人与心脏病风险:一项长达20年随访的队列研究

Veterans and risk of heart disease in the United States: a cohort with 20 years of follow up.

作者信息

Assari Shervin

机构信息

Department of Health Behavior and Health Education, Center for Research on Ethnicity, Culture, and Health, University of Michigan School of Public Health, Ann Arbor, MI, USA, Social Determinants of Health Research Center, University of Social Welfare and Rehabilitation, Tehran, Iran.

出版信息

Int J Prev Med. 2014 Jun;5(6):703-9.

Abstract

THE AIM OF THE CURRENT STUDY WAS TWOFOLD

To investigate the effect of veteran status on risk of developing heart disease over a period of 20 years in the United States and to test if socio-economic characteristics, chronic conditions, health behaviors, body mass index (BMI) and depressive symptoms explain the association between veteran status and risk of heart disease.

METHODS

Data came from the Health and Retirement Study, a 20 year national cohort from 1992 to 2012. The study enrolled a representative sample of Americans over the age of 50. We included 8,375 individuals who were older than 50 years at entry, did not have heart disease at baseline and provided data on heart disease over the next 20 years. Veteran status was considered to be the independent variable. Self-reported data on physician diagnosis of heart disease, which was measured on a biannual basis, was the outcome. Baseline socio-economic data (i.e. age, gender, race, marital status and education), chronic conditions (diabetes and hypertension), health behaviors (i.e. drinking, smoking, and exercise), BMI and depressive symptoms (modified Center for Epidemiologic Studies Depression Scale) were entered into logistic regressions. Logistic regression was used for data analysis.

RESULTS

Veterans were at higher risk of having a new onset of heart disease (unadjusted relative risk [RR] = 1.996, 95% confidence interval [CI] =1.694-2.351), compared with non-veterans. Logistic regression confirmed the association between veteran status and heart disease (adjusted RR = 1.483, 95% CI = 1.176-1.871) after controlling for all covariates.

CONCLUSIONS

Veterans may be at higher risk for heart disease over time and this link may be independent of baseline socio-economic characteristics, chronic medical conditions, health behaviors, BMI and depressive symptoms. Veterans may require more rigorous cardiovascular prevention programs.

摘要

本研究的目的有两个

调查在美国20年期间退伍军人身份对患心脏病风险的影响,并检验社会经济特征、慢性病、健康行为、体重指数(BMI)和抑郁症状是否能解释退伍军人身份与心脏病风险之间的关联。

方法

数据来自健康与退休研究,这是一个从1992年到2012年的20年全国队列研究。该研究纳入了50岁以上美国人的代表性样本。我们纳入了8375名在入组时年龄超过50岁、基线时没有心脏病且在接下来20年提供了心脏病相关数据的个体。退伍军人身份被视为自变量。以两年一次测量的医生诊断心脏病的自我报告数据为结果。将基线社会经济数据(即年龄、性别、种族、婚姻状况和教育程度)、慢性病(糖尿病和高血压)、健康行为(即饮酒、吸烟和锻炼)、BMI和抑郁症状(改良的流行病学研究中心抑郁量表)纳入逻辑回归分析。采用逻辑回归进行数据分析。

结果

与非退伍军人相比,退伍军人患新发心脏病的风险更高(未调整相对风险[RR]=1.996,95%置信区间[CI]=1.694 - 2.351)。在控制所有协变量后,逻辑回归证实了退伍军人身份与心脏病之间的关联(调整后RR = 1.483,95%CI = 1.176 - 1.871)。

结论

随着时间推移,退伍军人患心脏病的风险可能更高,并且这种关联可能独立于基线社会经济特征、慢性疾病状况、健康行为、BMI和抑郁症状。退伍军人可能需要更严格的心血管预防计划。

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