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通过分支DNA-金纳米聚集体的自组装实现癌细胞表面两种生物标志物的同步表面增强拉曼散射检测与成像。

Simultaneous SERS detection and imaging of two biomarkers on the cancer cell surface by self-assembly of branched DNA-gold nanoaggregates.

作者信息

Li Ying, Qi Xindi, Lei Chengcun, Yue Qifeng, Zhang Shusheng

机构信息

Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.

出版信息

Chem Commun (Camb). 2014 Sep 7;50(69):9907-9. doi: 10.1039/c4cc05226a.

Abstract

A surface-enhanced Raman scattering (SERS) method has been proposed for simultaneous detection and imaging of two biomarkers on the surface of a single human breast cancer cell (MCF-7) by self-assembly of branched DNA-gold nanoaggregates.

摘要

一种表面增强拉曼散射(SERS)方法已被提出,用于通过分支DNA-金纳米聚集体的自组装,对单个人类乳腺癌细胞(MCF-7)表面的两种生物标志物进行同时检测和成像。

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