Platt S D, Martin C J, Hunt S M, Lewis C W
Unit for Epidemiological Studies in Psychiatry, Royal Edinburgh Hospital.
BMJ. 1989 Jun 24;298(6689):1673-8. doi: 10.1136/bmj.298.6689.1673.
To examine the relation between damp and mould growth and symptomatic ill health.
Cross-sectional study of random sample of households containing children; separate and independent assessments of housing conditions (by surveyor) and health (structured interview by trained researcher).
Subjects' homes (in selected areas of public housing in Glasgow, Edinburgh, and London).
Adult respondents (94% women) and 1169 children living in 597 households.
Specific health symptoms and general evaluation of health among respondents and children over two weeks before interview; and score on general health questionnaire (only respondents).
Damp was found in 184 (30.8%) dwellings and actual mould growth in 274 (45.9%). Adult respondents living in damp and mouldy dwellings were likely to report more symptoms overall, including nausea and vomiting, blocked nose, breathlessness, backache, fainting, and bad nerves, than respondents in dry dwellings. Children living in damp and mouldy dwellings had a greater prevalence of respiratory symptoms (wheeze, sore throat, runny nose) and headaches and fever compared with those living in dry dwellings. The mean number of symptoms was higher in damp and mouldy houses and positively associated with increasing severity of dampness and mould (dose response relation). All these differences persisted after controlling for possible confounding factors such as household income, cigarette smoking, unemployment, and overcrowding. Other possible sources of bias that might invalidate the assumption of a causal link between housing conditions and ill health--namely, investigator bias, respondent bias, and selection bias--were also considered and ruled out.
Damp and mouldy living conditions have an adverse effect on symptomatic health, particularly among children.
研究潮湿与霉菌生长和有症状的健康问题之间的关系。
对有儿童家庭的随机样本进行横断面研究;对住房条件(由测量员进行)和健康状况(由经过培训的研究人员进行结构化访谈)进行单独且独立的评估。
受试者家中(在格拉斯哥、爱丁堡和伦敦公共住房的选定区域)。
成年受访者(94%为女性)以及居住在597户家庭中的1169名儿童。
访谈前两周内受访者和儿童的特定健康症状及健康总体评估;以及一般健康问卷得分(仅针对受访者)。
在184套(30.8%)住宅中发现潮湿,274套(45.9%)有实际霉菌生长。与居住在干燥住宅中的受访者相比,居住在潮湿且有霉菌的住宅中的成年受访者总体上可能报告更多症状,包括恶心、呕吐、鼻塞、呼吸急促、背痛、昏厥和神经紧张。与居住在干燥住宅中的儿童相比,居住在潮湿且有霉菌的住宅中的儿童呼吸道症状(喘息、喉咙痛、流鼻涕)、头痛和发烧的患病率更高。潮湿且有霉菌的房屋中症状的平均数量更高,且与潮湿和霉菌严重程度增加呈正相关(剂量反应关系)。在控制了家庭收入、吸烟、失业和过度拥挤等可能的混杂因素后,所有这些差异仍然存在。还考虑并排除了其他可能导致住房条件与健康问题之间因果关系假设无效的偏差来源,即调查者偏差、受访者偏差和选择偏差。
潮湿且有霉菌的生活环境对有症状的健康有不利影响,尤其是对儿童。