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芬兰家庭潮湿、霉菌及其对成年人呼吸道感染和症状的影响。

Home dampness, moulds and their influence on respiratory infections and symptoms in adults in Finland.

作者信息

Pirhonen I, Nevalainen A, Husman T, Pekkanen J

机构信息

Dept of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland.

出版信息

Eur Respir J. 1996 Dec;9(12):2618-22. doi: 10.1183/09031936.96.09122618.

Abstract

The aim of this study was to analyse the prevalence of mouldy homes and their association with respiratory symptoms and diseases in a subarctic climate. A questionnaire was mailed to a random sample of 2,000 males and females, aged 25-64 yrs, living in the county of Kuopio, Finland. A total of 1,521 (76%) responded and 1,460 were selected for the final analysis. The prevalence of homes with visible mould was 4%; with the odour of mould 5%; with damp spots, visible mould or the odour of mould 15%; and with moisture/ water damage, damp spots, visible mould or the odour of mould 23%. The number of reports of bronchitis, common cold, atopy, allergic rhinitis, rhinitis, fever and chills, hoarseness, fatigue, difficulties in concentration, lumbar backache and stomach ache were strongly associated with living in a damp home. Bronchitis, hoarseness and difficulties in concentration had the strongest associations, with adjusted odds ratios (95% confidence limits) of: 2.04 (1.49-2.78), 2.23 (1.37-3.63) and 2.17 (1.35-3.50), respectively. After controlling for a possible reporting bias by excluding those subjects reporting lumbar backache and recurrent stomach pain, eye irritation and tiredness remained significant. In conclusion, living in a home with mould problems may increase the risk of respiratory infections and symptoms in adults.

摘要

本研究旨在分析亚北极气候地区发霉房屋的患病率及其与呼吸道症状和疾病的关联。向居住在芬兰库奥皮奥县的2000名年龄在25 - 64岁之间的男性和女性随机样本邮寄了一份问卷。共有1521人(76%)回复,其中1460人被选入最终分析。有可见霉菌的房屋患病率为4%;有霉菌气味的为5%;有潮湿斑点、可见霉菌或霉菌气味的为15%;有潮湿/水损、潮湿斑点、可见霉菌或霉菌气味的为23%。支气管炎、普通感冒、特应性、过敏性鼻炎、鼻炎、发热寒战、声音嘶哑、疲劳、注意力不集中、腰背痛和胃痛的报告数量与居住在潮湿房屋中密切相关。支气管炎、声音嘶哑和注意力不集中的关联最为强烈,调整后的优势比(95%置信区间)分别为:2.04(1.49 - 2.78)、2.23(1.37 - 3.63)和2.17(1.35 - 3.50)。在排除报告腰背痛和反复胃痛的受试者以控制可能的报告偏倚后,眼睛刺激和疲劳仍具有显著性。总之,居住在有霉菌问题的房屋中可能会增加成年人呼吸道感染和出现症状的风险。

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