Grais Rebecca F, Juan-Giner Aitana
Epicentre, 8 rue Saint Sabin, Paris 75011, France
Epicentre, 8 rue Saint Sabin, Paris 75011, France International Vaccination Working Group, Médecins Sans Frontières, Paris, France.
Int Health. 2014 Sep;6(3):160-1. doi: 10.1093/inthealth/ihu051. Epub 2014 Aug 4.
There are more possible vaccination interventions to mitigate the adverse health consequences of populations in crises than ever before, but recent reviews suggest delivering these vaccines has been fraught with difficulty. The decision to implement vaccination interventions in crises remains, more often than not, an exercise in satisficing. The sparse credible epidemiologic and effectiveness data in populations affected by crises contributes greatly to decision-making difficulty, as do the limits of vaccine presentations, formulations and storage. Political considerations and lack of decision-making guidance contribute further. Moving forward requires sound effectiveness studies to help ensure that decision-making is based to the degree possible on substance.
与以往任何时候相比，现在有更多可能的疫苗接种干预措施来减轻处于危机中的人群的健康不良后果，但最近的综述表明，提供这些疫苗一直充满困难。在危机中实施疫苗接种干预措施的决定往往仍是一种满足现状的做法。受危机影响人群中稀少的可靠流行病学和有效性数据极大地增加了决策难度，疫苗的呈现形式、配方和储存的限制也是如此。政治因素和缺乏决策指导进一步加剧了这种情况。要取得进展，需要进行可靠的有效性研究，以帮助确保决策尽可能基于实质内容。
