Langeveld H R, Klitsie P, Smedinga H, Eker H, Van't Riet M, Weidema W, Vergouwe Y, Bonjer H J, Jeekel J, Lange J F
Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands,
Hernia. 2015 Aug;19(4):549-55. doi: 10.1007/s10029-014-1282-0. Epub 2014 Aug 5.
Chronic postoperative inguinal pain (CPIP) is considered the most common and serious long-term problem after inguinal hernia repair. Young age has been described as a risk factor for developing chronic pain after several surgical procedures. Our aim was to assess if age has prognostic value on CPIP.
The database of a randomized trial; the LEVEL trial, 669 patients, TEP versus Lichtenstein, was used for analysis. Data on incidence and intensity of preoperative pain, postoperative pain and CPIP at 1 year were collected. The association of age with incidence and intensity of pain was assessed with regression analysis. Further, hernia type and surgical technique were studied in combination with age and CPIP as possible risk factors on CPIP over age alone.
Younger patients (18-40 years) presented more often with CPIP than middle-aged patients (40-60 years) and elderly (>60 years); 43 vs. 29 vs. 19 %; overall 27 %. Younger and middle-aged patients had more frequently preoperative pain; 54 vs. 55 vs. 41 % and intensity of pain was higher during the first three postoperative days (VAS on day 1: 5.5 vs. 4.5 vs. 3.9 and on day 3: 3.8 vs. 2.9 vs. 2.6). Indirect-type hernias were seen more often in younger patients (77 vs. 51 vs. 48 %) and were not related to CPIP or with surgical technique.
Almost one out of three patients experiences CPIP. The younger the patient, the higher the risk of CPIP. Hernia type and surgical technique did not influence CPIP.
慢性术后腹股沟疼痛(CPIP)被认为是腹股沟疝修补术后最常见且严重的长期问题。在多种外科手术后,年轻被描述为发生慢性疼痛的一个风险因素。我们的目的是评估年龄对CPIP是否具有预后价值。
使用一项随机试验(LEVEL试验,669例患者,TEP与Lichtenstein术式对比)的数据库进行分析。收集术前疼痛、术后疼痛及1年时CPIP的发生率和强度的数据。通过回归分析评估年龄与疼痛发生率和强度之间的关联。此外,研究疝的类型和手术技术,并将其与年龄及CPIP相结合,作为单独年龄之外可能影响CPIP的风险因素。
年轻患者(18 - 40岁)发生CPIP的频率高于中年患者(40 - 60岁)和老年患者(>60岁);分别为43%、29%和19%;总体发生率为27%。年轻和中年患者术前疼痛更频繁;分别为54%、55%和41%,且术后前三天疼痛强度更高(第1天视觉模拟评分:5.5对4.5对3.9,第3天:3.8对2.9对2.6)。间接型疝在年轻患者中更常见(77%对51%对48%),且与CPIP或手术技术无关。
近三分之一的患者经历CPIP。患者越年轻,发生CPIP的风险越高。疝的类型和手术技术不影响CPIP。