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Does Type I Interferon Limit Protective Neutrophil Responses during Pulmonary Francisella Tularensis Infection?

作者信息

Furuya Yoichi, Steiner Donald, Metzger Dennis W

机构信息

Center for Immunology and Microbial Disease, Albany Medical College , Albany, NY , USA.

出版信息

Front Immunol. 2014 Jul 23;5:355. doi: 10.3389/fimmu.2014.00355. eCollection 2014.

DOI:10.3389/fimmu.2014.00355
PMID:25101094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4107939/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a635/4107939/7333a698b457/fimmu-05-00355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a635/4107939/7333a698b457/fimmu-05-00355-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a635/4107939/7333a698b457/fimmu-05-00355-g001.jpg

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本文引用的文献

1
Interleukin-17 protects against the Francisella tularensis live vaccine strain but not against a virulent F. tularensis type A strain.白细胞介素-17 可预防 弗氏柠檬酸杆菌活疫苗株,但不能预防毒力强的弗氏柠檬酸杆菌 A 型菌株。
Infect Immun. 2013 Sep;81(9):3099-105. doi: 10.1128/IAI.00203-13. Epub 2013 Jun 17.
2
Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.在体外和体内免疫研究中,弗氏柠檬酸杆菌获得的不一致结果归因于细菌结构完整性受损。
PLoS One. 2013;8(3):e58513. doi: 10.1371/journal.pone.0058513. Epub 2013 Mar 12.
3
mBio. 2019 Oct 8;10(5):e01223-19. doi: 10.1128/mBio.01223-19.
4
A Role for Neutrophils in Viral Respiratory Disease.中性粒细胞在病毒性呼吸道疾病中的作用
Front Immunol. 2017 May 12;8:550. doi: 10.3389/fimmu.2017.00550. eCollection 2017.
5
Mysteries of type I IFN response: benefits versus detriments.I型干扰素反应的奥秘:益处与损害
Front Immunol. 2015 Jan 28;6:21. doi: 10.3389/fimmu.2015.00021. eCollection 2015.
6
Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types.利用关于有益与有害的I型干扰素效应的机制知识,设计针对特定细胞类型细胞因子活性的创新免疫疗法。
Front Immunol. 2014 Oct 30;5:526. doi: 10.3389/fimmu.2014.00526. eCollection 2014.
Type I interferon induction during influenza virus infection increases susceptibility to secondary Streptococcus pneumoniae infection by negative regulation of γδ T cells.
流感病毒感染期间 I 型干扰素的诱导通过负向调节 γδ T 细胞增加了对二次肺炎链球菌感染的易感性。
J Virol. 2012 Nov;86(22):12304-12. doi: 10.1128/JVI.01269-12. Epub 2012 Sep 5.
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Bacteria-specific neutrophil dysfunction associated with interferon-stimulated gene expression in the acute respiratory distress syndrome.中性粒细胞针对细菌的功能障碍与急性呼吸窘迫综合征中干扰素刺激基因表达有关。
PLoS One. 2011;6(7):e21958. doi: 10.1371/journal.pone.0021958. Epub 2011 Jul 6.
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The involvement of IL-17A in the murine response to sub-lethal inhalational infection with Francisella tularensis.白细胞介素-17A 在感染弗氏志贺菌的小鼠亚致死吸入反应中的作用。
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Lung CD4-CD8- double-negative T cells are prominent producers of IL-17A and IFN-gamma during primary respiratory murine infection with Francisella tularensis live vaccine strain.在原发性肺部感染土拉弗朗西斯菌活疫苗株时,肺脏 CD4-CD8-双阴性 T 细胞是白细胞介素-17A 和干扰素-γ的主要产生细胞。
J Immunol. 2010 May 15;184(10):5791-801. doi: 10.4049/jimmunol.1000362. Epub 2010 Apr 14.
8
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis.AIM2 炎性小体对于机体对抗土拉弗朗西斯菌的固有免疫至关重要。
Nat Immunol. 2010 May;11(5):385-93. doi: 10.1038/ni.1859. Epub 2010 Mar 28.
9
Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections.I 型 IFN 信号在细菌感染过程中限制 gammadelta T 细胞分泌白介素-17A/F。
J Immunol. 2010 Apr 1;184(7):3755-67. doi: 10.4049/jimmunol.0902065. Epub 2010 Feb 22.
10
The roles of IL-17A in inflammatory immune responses and host defense against pathogens.白细胞介素-17A在炎症免疫反应及宿主抵御病原体过程中的作用。
Immunol Rev. 2008 Dec;226:57-79. doi: 10.1111/j.1600-065X.2008.00699.x.