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国内外资金投入对中低收入国家结核病防治的影响:2002-2011 年趋势分析及实现 2015 年目标所需资金。

Domestic and donor financing for tuberculosis care and control in low-income and middle-income countries: an analysis of trends, 2002-11, and requirements to meet 2015 targets.

机构信息

Global TB Programme, WHO, Geneva, Switzerland.

Global TB Programme, WHO, Geneva, Switzerland.

出版信息

Lancet Glob Health. 2013 Aug;1(2):e105-e115. doi: 10.1016/S2214-109X(13)70032-9. Epub 2013 Jul 24.

Abstract

BACKGROUND

Progress in tuberculosis control worldwide, including achievement of 2015 global targets, requires adequate financing sustained for many years. WHO began yearly monitoring of tuberculosis funding in 2002. We used data reported to WHO to analyse tuberculosis funding from governments and international donors (in real terms, constant 2011 US$) and associated progress in tuberculosis control in low-income and middle-income countries between 2002 and 2011. We then assessed funding needed to 2015 and how this funding could be mobilised.

METHODS

We included low-income and middle-income countries that reported data about financing for tuberculosis to WHO and had at least three observations between 2002 and 2011. When data were missing for specific country-year combinations, we imputed the missing data. We aggregated country-specific results for eight country groups defined according to income level, political and economic profile, geography, and tuberculosis burden. We compared absolute changes in total funding with those in the total number of patients successfully treated and did cross-country comparisons of cost per successfully treated patient relative to gross domestic product. We estimated funding needs for tuberculosis care and control for all low-income and middle-income countries to 2015, and compared these needs with domestic funding that could be mobilised.

FINDINGS

Total funding grew from $1·7 billion in 2002 to $4·4 billion in 2011. It was mostly spent on diagnosis and treatment of drug-susceptible tuberculosis. 43 million patients were successfully treated, usually for $100-500 per person in countries with high burdens of tuberculosis. Domestic funding rose from $1·5 billion to $3·9 billion per year, mostly in Brazil, Russia, India, China, and South Africa (BRICS), which collectively account for 45% of global cases, where national contributions accounted for more than 95% of yearly funding. Donor funding increased from $0·2 billion in 2002 to $0·5 billion in 2011, and accounted for a mean of 39% of funding in the 17 countries with the highest burdens (excluding BRICS) and a mean of 67% in low-income countries by 2011. BRICS and upper middle-income countries could mobilise almost all of their funding needs to 2015 from domestic sources. A full response to the tuberculosis epidemic to 2015, including investments to tackle multidrug-resistant tuberculosis, will require international donor funding of $1·6-2·3 billion each year.

INTERPRETATION

Funding for tuberculosis control increased substantially between 2002 and 2011, resulting in impressive and cost-effective gains. The increasing self-sufficiency of many countries, including BRICS, which account for almost half the world's tuberculosis cases, is a success story for control of tuberculosis. Nonetheless, international donor funding remains crucial in many countries and more is needed to achieve 2015 targets.

FUNDING

None.

摘要

背景

全球范围内的结核病控制取得了进展,包括实现 2015 年全球目标,这需要多年的充足资金支持。世卫组织从 2002 年开始每年监测结核病资金情况。我们利用向世卫组织报告的数据,分析了 2002 年至 2011 年期间,来自政府和国际捐助者(按 2011 年不变美元计算)的结核病资金以及低收入和中等收入国家结核病控制方面的进展情况。然后,我们评估了到 2015 年所需的资金以及如何筹集这些资金。

方法

我们纳入了向世卫组织报告结核病筹资情况且在 2002 年至 2011 年期间至少有 3 次观察数据的低收入和中等收入国家。当特定国家-年份组合的数据缺失时,我们采用了插补法。我们根据收入水平、政治和经济状况、地理位置和结核病负担,将国家特定结果汇总到八个国家组中。我们比较了总资金的绝对变化与成功治疗的患者总数的变化,并对每个成功治疗的患者相对于国内生产总值的治疗费用进行了跨国比较。我们估计了所有低收入和中等收入国家 2015 年结核病护理和控制所需的资金,并将这些需求与可调动的国内资金进行了比较。

结果

总资金从 2002 年的 17 亿美元增长到 2011 年的 44 亿美元。这些资金主要用于耐多药结核病的诊断和治疗。4300 万患者成功接受了治疗,在结核病负担较重的国家,通常每人花费 100-500 美元。国内资金从每年 15 亿美元增加到 39 亿美元,主要来自巴西、俄罗斯、印度、中国和南非(金砖国家),这五个国家共占全球病例的 45%,其国家捐款占每年资金的 95%以上。2002 年,捐助者资金从 2 亿美元增加到 5 亿美元,在负担最重的 17 个国家(不包括金砖国家),捐助者资金占资金总额的平均比例为 39%,到 2011 年,在低收入国家,捐助者资金占资金总额的平均比例为 67%。金砖国家和中高收入国家到 2015 年几乎可以从国内来源调动其所有资金需求。为应对 2015 年结核病流行,包括投资解决耐多药结核病问题,每年需要国际捐助者提供 16 亿至 23 亿美元的资金。

解释

2002 年至 2011 年期间,结核病控制资金大幅增加,取得了令人瞩目的、具有成本效益的成果。包括金砖国家在内的许多国家的自给自足能力不断增强,这些国家占全球结核病病例的近一半,这是结核病控制的一个成功案例。尽管如此,在许多国家,国际捐助者的资金仍然至关重要,需要更多资金才能实现 2015 年的目标。

资金来源

无。

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