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Clinical and microbiologic findings in six patients with erythema migrans of Lyme disease.

作者信息

Berger B W, Johnson R C

机构信息

Department of Dermatology, New York University School of Medicine, NY.

出版信息

J Am Acad Dermatol. 1989 Dec;21(6):1188-91. doi: 10.1016/s0190-9622(89)70327-3.

DOI:10.1016/s0190-9622(89)70327-3
PMID:2511231
Abstract

The clinical course of six patients with erythema migrans of Lyme disease was viewed in the context of antibiotic susceptibility studies of their own Borrelia burgdorferi isolates. An initial poor response by two patients to antibiotic therapy suggested the possibility of B. burgdorferi resistance to these agents. Minimum bactericidal concentration determinations of eight antimicrobial agents against these isolates did not support this suggestion.

摘要

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1
Clinical and microbiologic findings in six patients with erythema migrans of Lyme disease.
J Am Acad Dermatol. 1989 Dec;21(6):1188-91. doi: 10.1016/s0190-9622(89)70327-3.
2
In vitro susceptibility testing of Borrelia burgdorferi sensu lato isolates cultured from patients with erythema migrans before and after antimicrobial chemotherapy.对来自游走性红斑患者的伯氏疏螺旋体狭义种分离株在抗菌化疗前后进行体外药敏试验。
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Isolation of Borrelia burgdorferi sensu lato from blood of children with solitary erythema migrans.从患有孤立性游走性红斑的儿童血液中分离伯氏疏螺旋体狭义种。
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Cultivation of Borrelia burgdorferi from the blood of two patients with erythema migrans lesions lacking extracutaneous signs and symptoms of Lyme disease.从两名患有游走性红斑病变且无莱姆病皮肤外体征和症状的患者血液中培养出伯氏疏螺旋体。
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Detection of Borrelia burgdorferi-specific DNA in urine specimens from patients with erythema migrans before and after antibiotic therapy.在接受抗生素治疗前后,对游走性红斑患者尿液标本中伯氏疏螺旋体特异性DNA的检测。
J Clin Microbiol. 1996 Jun;34(6):1359-63. doi: 10.1128/jcm.34.6.1359-1363.1996.
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Failure to isolate Borrelia burgdorferi after antimicrobial therapy in culture-documented Lyme borreliosis associated with erythema migrans: report of a prospective study.在伴有游走性红斑的培养确诊莱姆病螺旋体病患者接受抗菌治疗后未能培养出伯氏疏螺旋体:一项前瞻性研究报告
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Treatment failure in erythema migrans--a review.游走性红斑的治疗失败——综述
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Risk of culture-confirmed borrelial persistence in patients treated for erythema migrans and possible mechanisms of resistance.游走性红斑患者经治疗后培养确诊的疏螺旋体持续存在风险及可能的耐药机制。
Int J Med Microbiol. 2006 May;296 Suppl 40:233-41. doi: 10.1016/j.ijmm.2006.01.028. Epub 2006 Mar 10.

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Current recommendations for the treatment of Lyme disease.
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