颅内记录与人类记忆。
Intracranial recordings and human memory.
作者信息
Johnson Elizabeth L, Knight Robert T
机构信息
Department of Psychology, University of California, Berkeley, United States; Helen Wills Neuroscience Institute, University of California, Berkeley, United States.
Department of Psychology, University of California, Berkeley, United States; Helen Wills Neuroscience Institute, University of California, Berkeley, United States.
出版信息
Curr Opin Neurobiol. 2015 Apr;31:18-25. doi: 10.1016/j.conb.2014.07.021. Epub 2014 Aug 14.
Recent work involving intracranial recording during human memory performance provides superb spatiotemporal resolution on mnemonic processes. These data demonstrate that the cortical regions identified in neuroimaging studies of memory fall into temporally distinct networks and the hippocampal theta activity reported in animal memory literature also plays a central role in human memory. Memory is linked to activity at multiple interacting frequencies, ranging from 1 to 500Hz. High-frequency responses and coupling between different frequencies suggest that frontal cortex activity is critical to human memory processes, as well as a potential key role for the thalamus in neocortical oscillations. Future research will inform unresolved questions in the neuroscience of human memory and guide creation of stimulation protocols to facilitate function in the damaged brain.
最近关于人类记忆表现时颅内记录的研究，为记忆过程提供了卓越的时空分辨率。这些数据表明，在记忆的神经影像学研究中确定的皮质区域可分为时间上不同的网络，动物记忆文献中报道的海马体θ活动在人类记忆中也起着核心作用。记忆与1至500赫兹范围内多个相互作用频率的活动相关联。高频反应以及不同频率之间的耦合表明，前额叶皮质活动对人类记忆过程至关重要，丘脑在新皮质振荡中也可能起着关键作用。未来的研究将为人类记忆神经科学中尚未解决的问题提供信息，并指导制定刺激方案以促进受损大脑的功能。
Zotero 插件