Lian C-h, Shen L-l, Gao Q-y, Jiang M, Zhao Z-j, Zhao J-j
Department of Dermatology, Shenzhen Second People's Hospital, Shenzhen, China.
Mycoses. 2014 Dec;57(12):759-64. doi: 10.1111/myc.12229. Epub 2014 Aug 15.
The genus Malassezia is important in the aetiology of facial seborrhoeic dermatitis (FSD), which is the most common clinical type. The purpose of this study was to analyse the distribution of Malassezia species in the facial lesions of Chinese seborrhoeic dermatitis (SD) patients and healthy individuals. Sixty-four isolates of Malassezia were isolated from FSD patients and 60 isolates from healthy individuals. Sequence analysis of the internal transcribed spacer (ITS) region was used to identify the isolates. The most frequently identified Malassezia species associated with FSD was M. furfur (76.56%), followed by M. sympodialis (12.50%) and M. japonica (9.38%). The most frequently isolated species in healthy individuals were M. furfur (61.67%), followed by M. sympodialis (25.00%), M. japonica (6.67%), M. globosa (3.33%), and M. obtusa (3.33%). Overall, our study revealed that while M. furfur is the predominant Malassezia species in Chinese SD patients, there is no significant difference in the distribution of Malassezia species between Chinese SD patients and healthy individuals.
马拉色菌属在面部脂溢性皮炎（FSD）的病因学中具有重要意义，FSD是最常见的临床类型。本研究的目的是分析马拉色菌种在中国脂溢性皮炎（SD）患者和健康个体面部皮损中的分布情况。从FSD患者中分离出64株马拉色菌，从健康个体中分离出60株。采用内转录间隔区（ITS）区域序列分析来鉴定分离株。与FSD相关的最常鉴定出的马拉色菌种是糠秕马拉色菌（76.56%），其次是合轴马拉色菌（12.50%）和日本马拉色菌（9.38%）。健康个体中最常分离出的菌种是糠秕马拉色菌（61.67%），其次是合轴马拉色菌（25.00%）、日本马拉色菌（6.67%）、球形马拉色菌（3.33%）和钝形马拉色菌（3.33%）。总体而言，我们的研究表明，虽然糠秕马拉色菌是中国SD患者中主要的马拉色菌种，但中国SD患者与健康个体之间马拉色菌种的分布没有显著差异。
