Federal University of Rio Grande do Norte.
Braz J Otorhinolaryngol. 2010 Mar-Apr;76(2):172-7. doi: 10.1590/S1808-86942010000200005.
Recently, the World Health Organization (WHO) excluded the desmoplastic pattern from the histopathological spectrum of solid ameloblastomas and classified it as a distinct variant, named desmoplastic ameloblastoma.
To perform a retrospective analysis of the clinicopathologic aspects in a case series of solid ameloblastomas.
Cross-sectional cohort study.
Data regarding age, gender, location and clinical characteristics were retrieved from patient records. Histological sections were evaluated regarding existing histological patterns and the predominant histological pattern. Cases were classified according to the study of Waldron and El-Mofty (1987) and the WHO classification of 2005.
A total of 54 cases were identified, with similar gender distribution and a mean age of 38.3 years. Fifty three cases (98.1%) affected the mandible. Forty nine cases (90.8%) were classified as solid ameloblastomas, 3 (5.6%) as desmoplastic ameloblastomas, and 2 (3.7%) as hybrid lesions. The most frequent histological patterns in solid ameloblastomas were follicular (77.6%), acanthomatous (69.4%), and plexiform (65.3%). Focal areas of desmoplastic ameloblastomas were identified in 11 solid ameloblastomas (22.4%).
Despite its characterization as a distinct variant, our results revealed that focal areas of desmoplastic ameloblastomas can be observed with some frequency in conventional ameloblastomas.
对一组成釉细胞瘤病例的临床病理方面进行回顾性分析。
横断面队列研究。
从患者病历中检索有关年龄、性别、部位和临床特征的数据。评估组织学切片中是否存在现有的组织学模式和主要的组织学模式。根据 Waldron 和 El-Mofty（1987 年）的研究和 2005 年世界卫生组织的分类对病例进行分类。
共确定了 54 例病例，性别分布相似，平均年龄为 38.3 岁。53 例（98.1%）发生在下颌骨。49 例（90.8%）被归类为成釉细胞瘤，3 例（5.6%）为促结缔组织增生型成釉细胞瘤，2 例（3.7%）为混合性病变。在成釉细胞瘤中最常见的组织学模式是滤泡型（77.6%）、棘皮瘤型（69.4%）和丛状型（65.3%）。在 11 例常规成釉细胞瘤中发现了局灶性促结缔组织增生型成釉细胞瘤区域（22.4%）。
尽管促结缔组织增生型成釉细胞瘤被认为是一种独特的变异型，但我们的结果表明，在常规成釉细胞瘤中，局灶性促结缔组织增生型成釉细胞瘤区域可能较为常见。
